Advanced Chemical Biology(Ⅰ) National Taiwan University

Course Overview
This class will discuss various special topics at the interface of chemistry and biology. 1. Nucleic acid structure and synthesis 2. DNA sequencing and mimetics 3. RNA: RNA interference 4. Ribozymes and aptamers 5. Carbohydrates: structure 6. Carbohydrates: biosynthesis and function 7. Carbohydrates: applications 8. Carbohydrates: chemical synthesis 9. Introduction to lipids and membranes 10. Lipid structure 11. Protein synthesis and folding 12. Protein degradation and quality control 13. Protein misfolding and neurodegeneration 14. Producing proteins and peptides 15. Chromatography and electrophoresis 16. Protein extraction, subcellular fractionation, centrifugation 17. Antibody technologies 18. Humanized antibody 19. Structural Biology 20. Labeling with fluorophores and biotin 21. Fluorescent proteins and FRET 22. Basics of Fluorescence Microscopy 23. Super-resolution Optical Microscopy 24. Bioorthogonal chemistry; Active site probe 25. Mass spec: instrumentation 26. Mass spec of proteins 27. Mass spec and protein quantification 28. Post-translational modifications
Learning Achievement
Understand the chemical principles behind the materials and methods commonly encountered in modern biology labs. Apply chemical thinking to solve biological problems.
Competence
Course prerequisites
*Majors-only (including minor and double major students). *Restrict to graduate students.
Grading Philosophy
Course schedule
Course type
Online Course Requirement
Instructor
Hwan-Ching Tai
Other information
Division of Chemical Biology
Site for Inquiry
Please inquire about the courses at the address below.
Email address: http://www.ch.ntu.edu.tw/english/en_index.htm