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Course Detail

Degree
Bachelor
Standard Academic Year
Course delivery methods
face-to-face
Subject
Biological sciences
Program
School
College of Bio-Resources & Agriculture
Department
Campus
Classroom
Course Offering Year
Course Offering Month
September - November
Weekday and Period
Monday 234
Capacity
Credits
3
Language
English
Course Number
Biot8016

Advanced Small Rna and Mechanism of Gene Silencing National Taiwan University

Course Overview

COURSE DESCRIPTION: THIS HALF-YEAR GRADUATE COURSE AIMS TO INTRODUCE BASIC GENE SILENCING CONCEPTS AND RESEARCH TECHNIQUES AVAILABLE TO ADDRESS GENE SILENCING QUESTIONS IN PLANT AS WELL AS OTHER ORGANISMS. STUDENTS ARE EXPECTED TO DEVELOP THE ABILITY TO CRITICALLY EVALUATE AND INTERPRET PUBLISHED RESEARCH ARTICLES. THEY WILL ALSO LEARN TO EXTRACT INFORMATION FROM INTERNATIONAL CONFERENCES BY LISTENING TO EXPERTS OF EACH FIELD INTRODUCING THEIR RESEARCH. OUTLINE: 1. INTRODUCTION - OVERVIEW 2. SENSE CO-SUPPRESSION IN PLANT 3. TRANSGENE CO-SUPPRESSION IN ANIMALS 4. PLANT VIRUS RESISTANCE VS. CO-SUPPRESSION 5. TRANSCRIPTIONAL GENE SILENCING (TGS) 6. POST-TRANSCRIPTIONAL GENE SILENCING (PTGS) 7. VIRUS-INDUCE GENE SILENCING (VIGS) 8. SILENCING SIGNAL TRANSPORTATION 9. SMALL RNA 10. SIRNA PATHWAY 11. MIRNA PATHWAY 12. FUNCTION OF DICER 13. FUNCTION OF RNA-INDUCE SILENCING COMPLEX (RISC) 14. FUNCTIONS OF DICER-LIKE PROTEINS (DCLS) IN PLANT 15. DCL1 VS. MIRNA BIOGENESIS 16. FUNCTION OF DCL2 AND NAT-SIRNA 17. FUNCTION OF DCL3 AND DNA METHYLATION 18. FUNCTION OF DCL4 AND TRANS-SIRNA 19. ARGONATURE FAMILY 20. SUPPRESSION OF GENE SILENCING 21. RNAI TECHNOLOGY 22. MIRNA TECHNOLOGY

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