Cell Physiology: Neuronal and hormonal communication University of Bordeaux
Course objective: - Study the two main long distance communication systems ofvertebrates : the nervous and endocrine systems.
- B2 level of English. - First Bachelor year in a similar discipline with knowledge inCellular Biology and notions of Physiology
In December or January: - 1h30 final exam on the Lectures (coef 0.6) - 1h30 final exam onthe tutorials and practicals (coef. 0.4)
Introduction: nervous system and hormonal systems:similarities,differences, interactions between the two systemsPlasma membranereminders: structure; function / transport 1) THE NERVOUS SYSTEM- Structure of the nervous system (central and peripheral) - Theneuron: structure, properties. - Ion exchanges through the membrane(channels, pumps),electrochemical equilibrium potential of an ion. - The membrane potential; The Resting potential of excitablecells - Action potential: ionic theory, ion channels involved,properties,propagation. - Neurotransmission. The electrical synapse(structure, role).The chemical synapse: from neurotransmitters releasetopostsynaptic potentials (IPSP, EPSP, End-plate potentialandpostsynaptic integration); Ionotropic receptors (egnicotiniccholinergic receptor); Metabotropic receptors(example: modulation of the cardiac activity: cholinergic muscarinicandbeta-adrenergic receptors). 2) The striated muscle.Excitation-contraction coupling. 3) Introduction to endocrinology- General introduction to hormonal systems - Hypothalamic-pituitarycomplex; endocrine glands - Mechanism of action of hydrophilic(peptides) vshydrophobic hormones (steroids ...) - Example ofhormonal regulation: regulation of blood glucoseby the pancreas Example of a physiological reaction involving the twosystems: reactionto stress: activation of the hypothalamicpituitary-adrenal axis andsympathetic nervous system(noradrenaline - adrenaline - cortisol).
Lectures (22h), Tutorials (16h) and experiments usingcomputer simulation (6h)
Online Course Requirement
Duration: One semesterLanguage of instruction: English
Site for Inquiry
Please inquire about the courses at the address below.
Contact person: Denis Combesdenis.firstname.lastname@example.orgSophie Javerzatsophie.email@example.comPhilippe Gallusci firstname.lastname@example.org