Epigenetics and cell differentiation Université Grenoble Alpes
Course outline Today, the term “epigenetics” is used to describe the study of heritable changes in genome function that occur without a change in DNA sequence. This includes the way gene expression is passed from one cell to its progeny, how gene expression changes during the differentiation of one cell type into another, and how environmental factors can change the way genes are expressed. Epigenetic regulation involves changes of chromatin structure. Interestingly, the mechanisms involved in epigenetic regulation, such as histone modifications, also participate in the transient changes of gene expression. This course is therefore opened to all students with an interest in the control of gene expression. There are far-reaching implications of epigenetic research for plant and human biology and disease. The different mechanisms involved in epigenetic regulation, and the different contexts involving epigenetic regulation will be presented: - actors involved in epigenetic regulation (role of histone modification, chromatin remodeling complex, histone variants, DNA methylation, small and long noncoding RNA), - contexts involving an epigenetic regulation (response to cell environment, cell differentiation, development) - implication in diseases.
Online Course Requirement
Course content can evolve at any time before the start of the course. It is strongly recommended to discuss with the course contact about the detailed program.
Please consider the following deadlines for inbound mobility to Grenoble:
- April 1st, 2020 for Full Year (September to June) and Fall Semester (September to January) intake ;
- September 1st, 2020 for Spring Semester intake (February – June).
Site for Inquiry
Please inquire about the courses at the address below.
Contact person: Agnès VERE