Course Overview

課程名稱: 細胞微機電及微流體導論 (Introduction to Cellular BioMEMS and Biomicrofluidics) 1.Cellular biomechanics: anatomy and physiology of cells, mechanics of cytoskeleton, cell-matrix interaction, focal adhesions, mechanical model, mechanoreceptors, mechanical behavior of cells: mitosis, migration, and introduction to infection induced cell abnormality. 2.Tissue Engineering: microcirculation, capillary anatomy, diffusion and convection, Starling law, osmotic pressure, interstitial flow, basics of angiogenesis and vasculogenesis. 3.BioMEMS: Photolithography, bulk micromachining, surface micromachining, micro-molding, plastic manufacturing. 4.Microfluidics: scaling laws, surface to volume ratio, hydraulic resistance, wall shear stress, diffusion, capillary flow, hydrodynamics in porous media. 5.Special topic: Cell-based chip for biotechnology - bioreactors, studies of mechanics of abnormal cells, cell sorting, cell trapping. 6.Special topic: BioMEMS for cell biology - substrate dependency of cells, cell-cell contact, cell migration. 7.Special topic: Tissue microengineering - 3D culture, angiogenesis, vasculogenesis, organ on a chip.

Learning Achievement

(1) Introduce how to use basic mechanics to explain cell and tissue mechanics. (2) Explain how to apply cell mechanics to the design of BioMEMS and Biomicrofluidic devices (3) Understand the applications of BioMEMS and Biomicrofluidics in medical applications

Competence

Course prerequisites

Grading Philosophy

Course schedule

Course type

Online Course Requirement

Instructor

Yu-Hsiang Hsu

Other information

Non-degree Program: Nano-Technology Engineering,
(College of Engineering) Graduate Institute of Applied Mechanics

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