Course Overview

This course presents the fundamental principles of research and
development of analytical chemistry methods, with different examples
of instruments, methods and applications in the pharmaceutical field

Learning Achievement

Competence

Course prerequisites

- hold a Bachelor or first year of master in pharmacy, chemistry or
engineer 
- English level: B2 
- Computer with a word processor and internet connection

Grading Philosophy

Module 1: Mass spectrometry 
- 2 Reports on lab work1h25 % weight of overall mark  - Written
exam*2h50% weight of overall mark  Module 2: Capillary
electrophoresis 

- Report on the lab work2h25% weight of overall mark  - Written
exam*2h50% weight of overall mark Module 3: Spectroscopy and
spectrophotometry 

- Written exam*2h50% weight of overall mark  Module 4: Advanced
liquid chromatography 

- Written exam*2h50% weight of overall mark *A unique written exam for
the teaching unit  RULES AND PROTOCOL FOR FAILURES 
- Overall mark ≥ 10/20  - Module mark ≥ 7.5/20

Course schedule

Module 1: Mass spectrometry 
- Definitions and principles  - Ionization sources - Analysers and
detectors - Rules of fragmentation  - Pharmaceutical applications 
Module 2: Capillary electrophoresis 

- Introduction (instrumentation, benefits, drawbacks, applications) -
Fundamental principles (electrophoretic migration and electroosmotic
flow, parameters impacting migration and flow, dispersion sources,
injection modes)  - Separation modesCapillary Zone
ElectrophoresisMicellar Electrokinetic ChromatographyChiral analysis 
Module 3: Spectroscopy and spectrophotometry 

- Raman Spectroscopy  - Infrared and near infrared spectroscopy  -
UV-Visible spectrophotometry  - Fluorescence spectroscopy  Module
4: Advanced liquid chromatography 

- U(H)PLC method transfer  - Detectors  - Separation techniques 
- Ion chromatography  - Ion exchange chromatography  -
Hydrophilic interaction chromatography  - Hydrophobic interaction
chromatography  - Size exclusion Chromatography

Course type

- Lectures and tutorial in remote (Zoom and Moodle)  - Face-to-face lectures, tutorial and practice -  Distance-based: 10h lectures and 6h tutorials  - Face to face teaching: 14h lectures, 2h tutorials and 28h practice

Online Course Requirement

Instructor

Other information

- Maximum number of students: 30 
- Selection procedure: online application + interview 
- Selection criteria: solid bases in analytical chemistry and
chromatography, the adequacy of the initial training, professional
experience and professional project 

Duration: 24h lectures, 8h tutorials and 28h practice

Language of instruction: English
Mode of delivery: Face-to-face teaching and distance-based

Site for Inquiry