This course is designed based on the teaching method of “authentic learning” to guide students to learn about the applications of statistics in marine chemistry. Basic statistics will be introduced with real-world marine chemical data sets. This course is complementary to the mandatory course “NTU Fundamentals of Oceanic Statistics” (基礎海洋統計) and to the Marine Chemistry Laboratory (海洋化學實習) for students in the chemical oceanography division.

A variety of data set from analytical methods including spectrophotometry, chromatography, mass spectrometry, chemiluminescent, fluorimeter, optical sensor and pH sensors, commonly used by chemical oceanographers. While the principles of analysis differs significantly among analytical methods, it is important that students be versatile in dealing with various data set. For example, spectrophotometry is a basic method for the analyses of marine micro nutrients, its sensitivity and stability can be directly estimated based on the extinction coefficient—the intensiveness of the color. The limit of detection is a fixed value. While other instruments such as a mass spectrometer, can be tuned in a various ways to provide a better sensitivities, different labs report different limits of detection. While the cost of an analysis using a spectrophotometer is only 1/1000 of the cost using a mass spectrometer, by using statistic tools and the combination of knowledge in analytical chemistry, students will learn to choose the most suitable method for their research.

The course will start by having students to look for problems in a reported data set. For example, a figure of data points without the report of error bars. Students will have to explore possible ways to estimate the errors. We will then discuss how to design experiments to measure the uncertainties. The course will then provide data from spectrophotometry, chromatography, mass spectrometry, chemiluminescent, fluorimeter, optical sensor and pH sensors, for students to report the data in a statistically acceptable way.

A variety of data set from analytical methods including spectrophotometry, chromatography, mass spectrometry, chemiluminescent, fluorimeter, optical sensor and pH sensors, commonly used by chemical oceanographers. While the principles of analysis differs significantly among analytical methods, it is important that students be versatile in dealing with various data set. For example, spectrophotometry is a basic method for the analyses of marine micro nutrients, its sensitivity and stability can be directly estimated based on the extinction coefficientthe intensiveness of the color. The limit of detection is a fixed value. WhWhile other instruments such as a mass spectrometer, can be tuned in a various ways to provide a better sensitivities, different labs report different limits of detection. While the cost of an analysis using a spectrophotometer is only 1/1000 of the cost using a mass spectrometer, by using statistic tools and the combination of knowledge in analytical chemistry, students will learn to choose the most suitable method for their research.

The course will start by having students to look for problems in a reported data set. For example, a figure of data points without the report of error bars. Students will have to explore possible ways to estimate the errors. We will then discuss how to design experiments to measure the uncertainties. The course will then provide data from spectrophotometry, chromatography, mass spectrometry, chemiluminescent, fluorimeter, optical sensor and pH sensors, for students to report the data in a statistically acceptable way.

(1) Students will know about basic statistics for chemical oceanographic data.

– Numbers of replicates

– Limit of detection

– Sensitivity

– Error analysis

– Outliers

– Significance tests

– Distribution patterns

– Principle component analysis

– Factor analysis

(2) Students will be able to identify problems in reported data set.

(3) Students will have the capability to use statistical tools to explore their research data.

College of Science Main Campus *Chinese may be used when no international students sign up for this course. Huei-Ting Lin 10 Friday 1,2 Ocean5106 2 Half Graduate Institute of Oceanography, Chemical Oceanography Division http://www.oc.ntu.edu.tw/?lang=en

This class will discuss various special topics at the interface of chemistry and biology.

1. Nucleic acid structure and synthesis

2. DNA sequencing and mimetics

3. RNA: RNA interference

4. Ribozymes and aptamers

5. Carbohydrates: structure

6. Carbohydrates: biosynthesis and function

7. Carbohydrates: applications

8. Carbohydrates: chemical synthesis

9. Introduction to lipids and membranes

10. Lipid structure

11. Protein synthesis and folding

12. Protein degradation and quality control

13. Protein misfolding and neurodegeneration

14. Producing proteins and peptides

15. Chromatography and electrophoresis

16. Protein extraction, subcellular fractionation, centrifugation

17. Antibody technologies

18. Humanized antibody

19. Structural Biology

20. Labeling with fluorophores and biotin

21. Fluorescent proteins and FRET

22. Basics of Fluorescence Microscopy

23. Super-resolution Optical Microscopy

24. Bioorthogonal chemistry; Active site probe

25. Mass spec: instrumentation

26. Mass spec of proteins

27. Mass spec and protein quantification

28. Post-translational modifications

Understand the chemical principles behind the materials and methods commonly encountered in modern biology labs. Apply chemical thinking to solve biological problems. College of Science Main Campus *Majors-only (including minor and double major students).
*Restrict to graduate students. Hwan-Ching Tai 50 Monday 6,7 Thursday 6,7 Chem7037 4 Half Division of Chemical Biology http://www.ch.ntu.edu.tw/english/en_index.htm

This course focuses on the neural basis of language. It addresses how the brain works to process speaking, reading, and understanding language in human beings. It emphasizes how neuro-imaging data are used to form the theories of language. I will present empirical evidence of conventional psycholinguistic studies and recent imaging findings. The aim of this course is to provide an integrative overview of how the components of the language system combine together. Students are required to take part weekly article presentations. College of Science Main Campus Tai-Li Chou 15 Wednesday 2,3,4 Psy5274 3 Half Department of Psychology,
Graduate Institute of Psychology,
Program of Neurobiology and Cognitive Science
http://140.112.62.170/index.php/eng

Designed for doctoral and masters students, this seminar focuses on manuscript writing for an international journal. The seminar consists of three components. The goals of this seminar are for each student to (1) understand the process of putting together a manuscript for submission to an international journal and (2) write a draft of a manuscript or sections of a manuscript. College of Science Main Campus Kang-Tsung Chang 15 Thursday 2,3,4 Geog8020 3 Half Graduate Institute of Geography http://www.geog.ntu.edu.tw/index.php?lang=en

This is a course intended for students with basic knowledge of ecology, statistics, differential equations, and computer programming techniques and had some experience on modeling. We will discuss the application of mathematical modeling and computer programming techniques to investigate ecological questions. We will also discuss statistical analyses for identifying ecological patterns. Students will select a subject base on his/her own interest and present the progress of the chosen topic. The class is mainly in the form of discussion. Students are required to do oral presentation on a topic of ecological modeling and participate discussion. College of Science Main Campus Takeshi Miki 25 Tuesday 7,8 Ocean7152 2 Half Graduate Institute of Oceanography, Marine Biology & Fisheries Division http://www.oc.ntu.edu.tw/?lang=en

This course offers a balanced, stimulating survey of marine ecology, introducing the key processes and systems from which the marine environment is formed, and the issues and challenges which surround its future conservation.

In general, we will meet 2 hours (Mon 13:20 – 15:10) every week, but occasionally we may watch documentary on the 3rd hours.

For the week 8 and 10, instead of meeting in the classroom, we will spend half day in Mangrove ecocenter and full day in NMMST to discuss the course materials and to explore the environment.

Students are expected to develop a broad understanding on various issues of marine ecology, be able to generate an in-depth review on a selected topic and give a presentation. College of Science Main Campus Chih-Lin Wei 15 Monday 6,7,8 Ocean5002 3 Half Graduate Institute of Oceanography, Marine Biology & Fisheries Division,
Introductory Course of Marine Science http://www.oc.ntu.edu.tw/?lang=en

This is an introductory course intended for undergraduate and graduate students with knowledge of basic ecology. The focus will be on OCEANOGRAPHY, with investigation on interactive biological, chemical, and physical processes in the ocean. The purposes are to give an overview of biological ocean science (a wide rather than deep view) and to provide basic information and training for graduate research. The discussion will range from physical effects on the biology to biological effects on biogeochemical cycling; the spatial scale will range from individual organisms (e.g. viscosity and turbulences on plankton feeding and nutrient uptake) to ecosystem (e.g. remote sensing and circulation modeling); the organism will range from virus to whales. Students will gain knowledge of biological oceanography College of Science Main Campus Chih-Hao Hsieh 25 Tuesday 2,3,4 Ocean5051 3 Half Graduate Institute of Oceanography, Marine Biology & Fisheries Division,

Earth System Science,

Sustainable Development Resource,

Introductory Course of Marine Science
http://www.oc.ntu.edu.tw/?lang=en

Learning the subject of elementary particle physics Get familiar with the standard model of particle physics, Feynman diagrams, Feynman rules, calculations of elementary particle processes. College of Science Main Campus Cheng-Wei Chiang 30 Tuesday 3,4,5 Phys8033 3 Half Graduate Institute of Physics http://www.phys.ntu.edu.tw/webeng/APHome.aspx

Syllabus

1. Establishing Background: solid state physics and advanced materials (I)

2. Establishing Background: solid state physics and advanced materials (II)

3. Introduction (TLS/TPS)

4. X-ray Photoemission Spectroscopy (XPS) (soft x-ray)

5. Angular resolved photoemission (APES) (soft x-ray)

6. X-ray absorption spectroscopy (XAS) (soft x-ray)

7. X-ray magnetic circular dichroism (XMCD) (soft x-ray)

8. X-ray microscopy: PEEM/SR-STM/SPEM/STXM (soft x-ray) (I)

9. X-ray microscopy: PEEM/SR-STM/SPEM/STXM (soft x-ray) (II)

10. X-ray diffraction/scattering (hard x-ray)

11. Synchrotron for Biophysics (hard/soft x-ray)

12. Introduction to Neutron production and selected techniques

13. Neutron diffraction/scattering

14. Special Topic: XMCD-PEEM/SPEM

15. NSRRC Lab Tour

16. Presentations / Final Exam

Syllabus

1. Establishing Background: solid state physics and advanced materials (I)

2. Establishing Background: solid state physics and advanced materials (II)

3. Introduction (TLS/TPS)

4. X-ray Photoemission Spectroscopy (XPS) (soft x-ray)

5. Angular resolved photoemission (APES) (soft x-ray)

6. X-ray absorption spectroscopy (XAS) (soft x-ray)

7. X-ray magnetic circular dichroism (XMCD) (soft x-ray)

8. X-ray microscopy: PEEM/SR-STM/SPEM/STXM (soft x-ray) (I)

9. X-ray microscopy: PEEM/SR-STM/SPEM/STXM (soft x-ray) (II)

10. X-ray diffraction/scattering (hard x-ray)

11. Synchrotron for Biophysics (hard/soft x-ray)

12. Introduction to Neutron production and selected techniques

13. Neutron diffraction/scattering

14. Special Topic: XMCD-PEEM/SPEM

15. NSRRC Lab Tour

16. Presentations / Final Exam

College of Science Main Campus Minn Tsong Lin 30 Thursday 7,8 Phys8121 2 Half Graduate Institute of Physics,
Graduate Institute of Applied Physics http://www.phys.ntu.edu.tw/webeng/APHome.aspx

Purpose of the course:

The course is intended to give the students a basic training in quantum mechanics. In the first semester we learned the necessary mathematical tools, developed the subject from the postulates of quantum mechanics, and addressed the indispensable preliminaries. In this coming second semester of the course, the emphasis of the course will be on the second half of the following textbook.

Textbook:`Principles of Quantum Mechanics`, Second Edition, by R. Shankar, (Plenum)
Subjects to be covered:
a) Symmetry and their consequences
b) Rotational invariance and angular momentum
c) The hydrogen atom
d) Spin
e) Addition of angular momenta
f) Variational and WKB methods
g) Perturbation theories
h) Scattering theory

References: `Quantum Physics`, Second Edition, by Stephen Gasiorowicz, (Wiley)
College of Science Main Campus Ching Teh Li 20 Tuesday 3,4,5 Phys8067 3 Full Graduate Institute of Physics,
Tigp-Molecular Science and Technology http://www.phys.ntu.edu.tw/webeng/APHome.aspx

This course covers the principles and methods of equilibrium statistical mechanics for applications to chemical physics problems. The lectures will be divided into three parts: a short review of thermodynamics principles, the concepts of ensemble theory and the applications to gas, liquid, solution and solid systems. The final part will introduce the phase transition and the theory of Brownian motion.

Planned topics: laws of thermodynamics, thermal equilibrium and temperature, ensemble theory, entropy, non-interacting systems (gas and solid), chemical equilibrium, imperfect gases, classical liquids, ionic and non-ionic solutions, Ising models. Langevin equation and Brownian motion. This course aims to introduce basic concepts of equilibrium statistical mechanics for physical chemistry in the graduate level. College of Science Main Campus *Majors-only (including minor and double major students). Yuan-Chung Cheng 20 Tuesday 6,7,8 Chem7031 3 Half Division of Chemistry http://www.ch.ntu.edu.tw/english/en_index.htm

Outline

I. Symmetry & Bonding

Molecular Geometry, Symmetry Elements & Operations, Point Groups,

Representation & Character Tables, Applications to Spectroscopies

Symmetry-adapted Linear Combinations

Linear Combination of Atomic Orbitals

Molecular Orbital Theory for ABn Type Molecules

Tanabe and Sugano Diagrams, Walsh Diagrams

II. Transition Metal Chemistry

Electronic Configuration, Spectroscopy, Magnetism

Coordination Chemistry

Bonding, Structures, Reactivity & Reaction Mechanisms

III. Main Group Chemistry

Ionic & Covalent Bond, Chemical Forces, H-Bonding & Acid-Base

Chemistry

Structures & Reactivity

Supramolecular Chemistry & Organometallic Chemistry

A Brief Introduction on Modern Development


Bonding, Structure, Reactivity, Mechanism, and Applications of Inorganic Compounds College of Science Main Campus *Majors-only (including minor and double major students).
*Restrict to graduate students. Kong Kien Voon 50 Wednesday 6,7,8 Chem7029 3 Half Division of Chemistry http://www.ch.ntu.edu.tw/english/en_index.htm