This is a basic introductory course for Behavior Analysis principles. In this sense, it aims to provide the basic requirements for the student to understand the experimental and conceptual foundations of Behavior Analysis, so that the graduate student is able to attend other disciplines in the program. At the end of the course, it is expected that students are able to: 1. Identify the main concepts of behavior analysis; 2. Analyze behavior using such concepts; 3. Perform laboratory experiments with human subjects and/or animals, formulate the research question, the experimental design, collect and analyze data. 4. Prepare scientific reports following international publishing standards Institute of Psychology (IP) São Paulo main campus Theoretical part: 1. Selection by consequences (phylogenetic, ontogenetic and cultural levels); 2. Response Consequences: reinforcement (positive and negative) 3. Response Consequences: punishment (positive and negative); 4. Secondary Reinforcement; 5. Schedules of reinforcement; 6. Stimulus Control; 7. Discrimination and Generalization; 8. Equivalence Stimuli Classes; 9. Verbal Behavior; 10. Rule Governed Behavior; 11. Social Contingencies; 12. The Evolution of Cultural Practices. Practical Part: Developing a research involving animals and/or humans. Animal research is conducted in operant conditioning lab using rats and involves observation and registration of operant level, shaping lever press, establishing stimulus control and performances under schedules of reinforcement. Research with human involves complex stimulus control, verbal behavior and/or cultural selection Maria Martha Costa H_bner, Paula Debert, Marcelo Frota Lobato Benvenuti 22 PSE5750 12 Seminars; – Exams – Research Report http://www.ip.usp.br/psiclin/index.php?option=com_content&view=frontpage&lang=en

Over the last two decades, Experimental Psychology and Behavioral Neurosciences have benefited intensely from research in Cognitive Psycholinguistics. The present discipline is rooted in solid field experience and aims at introducing students to the main contemporary paradigms and publications, helping them to plan and conduct experiments, and publish research findings in the area. The Cognitive Neuropsycholinguistics Laboratory provides equipment and support for research and development in the areas of sensory impairments (deafness and blindness), motor impairments (cerebral palsy, muscular dystrophy), language disorders (aphasia, dyslexia), as well as a vast arsenal of instruments for assessment and intervention in language development and disorders in speech, sign language, reading and spelling, that are typical of those disorders. Introducing students to t theoretical approaches and experimental designs for research in cognitive psycholinguistics. Teaching them to use instruments to assess and intervene in developmental parameters of cognitive competencies involving speech, sign language, reading and spelling in the school setting, and to use instruments and procedures for differential diagnosis and treatment of language impairments and disorders involving speech, sign language, reading and spelling in daily practice. Teaching students to plan and conduct experimental studies in speech, sign language, reading and spelling. Institute of Psychology (IP) São Paulo main campus 1- Hemispheric specialization, structure and processing of language and imagery.2- Iconic and linguistic representation and processing. Phonics and imagery. 3- Reception, processing, and expression on speech, sign language, and writing. 4- Memory structure and processes. Sensorial memory: iconic and echoic. Working memory. Long term memory. 5- Information rehearsal. Storage and retrieval processes. Phonological loop. Visoespatial sketchboard. Fading, displacement, and consolidation processes. 6- First language development and disorders in speech and sign language. 7- Second language development and disorders in speech and writing: Deaf literacy acquisition and disorders. 8- Neuropsychological assessment and intervention in brain lesion. 9- Neuropsychological assessment in sensory impairments, as well as in motor and language disorders. 10- Information processing in Deafness (congenital versus acquired), dyslexia (developmental versus acquired), cerebral palsy, aphasias (global, subcortical, Broca, Wernicke, transcortical). 11- Assessment and intervention in language disorders involving phonetics, phonology, orthography, lexical and memory processes. 12- Phonetics, phonology, and orthography of Brazilian Portuguese: pronunciation and spelling. 13- Waveform analyses in speech production as a means of assessing phonological and lexical reading processes. 14-Assessment and intervention in developmental and acquired dyslexia and dysorthography. 15- Assessment and intervention in in deaf and hearing aphasics. Fernando Cesar Capovilla 22 PSE5819 8 Two Exams: one mid-term exam, and one final exam. http://www.ip.usp.br/psiclin/index.php?option=com_content&view=frontpage&lang=en

The aim of this discipline is to present the students seminal papers of molecular biology. These papers will be analysed from a historical, methodological and scientific perspective. This discipline complements the basic knowledge acquired in regular disciplines of molecular biology. By discussing original articles, the students will analyze in depth the historical context and the methodologies used by the scientists that pave the way of molecular biology. This will ultimately give the students the tools to understand the basis of molecular biology and the development of scientific thought. Biomedical Sciences Institute (ICB) São Paulo main campus Every lecture will be followed by the discussion of an original article. The student will receive a questionnaire that will guide him/her through the reading of the paper, with the help of the instructors. Items to be discussed include the following topics: (1) Structure and function of DNA ; ( 2 ) RNA and the genetic code ; ( 3 ) Advent of genetic engineering and genomics. Carlos Eduardo Winter, Beny Spira 25 ICB5751 8 Written tests will be used to evaluate student progress during the course. https://ww2.icb.usp.br/ing/

Many fields of biological research have changed markedly over the past few years with the rise of high-throughput laboratory techniques such as microarrays, massive nucleic acid sequencing and proteomic technologies. These technical developments have brought forth not only a significant, and still ongoing, change in philosophical outlook, but have also transformed how work in certain fields is performed in the lab _ more specifically, the computer lab. Generation of huge data files that are only useful after extensive computational processing became a frequent task in many biological research groups. Proper training in basic computational concepts and tools that can greatly aid in such endeavors have thus become essential in order to extract all the information that many modern large-scale techniques of biological research can provide. This course’s goal is to provide intensive and advanced training in computer usage on the command-line interface (CLI) for large-scale data analysis. At the end of the course, students from biologically-oriented backgrounds should be able to use the CLI to view, edit, manipulate, and summarize large data files, successfully extracting biological information and insight from the high-throughput analyses that generated those files. Biomedical Sciences Institute (ICB) São Paulo main campus • Introduction to computers and the Unix family of operating systems. • Accessing the shell (Bash), locally or remotely, and Bash basics. • Getting help with man, info, apropos, and Internet search engines. • Moving around the directory tree; finding and executing programs; navigating/understanding the system (memory, disk space etc.). • System structure; file types; user and group permission model; Changing file access (owner, group, permissions). • Standard streams and redirection; piping. • Finding and manipulating files and directories (create, delete, move, copy, rename, append, concatenate etc.). • Describing and summarizing file content (wc, file); getting data into the system (wget, scp, ftp). • Creating, exploring, and sub-setting files. • Comparing, sorting, and editing files. • Compressing and decompressing data (tar, gz, zip etc.). • Basics of regular expressions. • Compiling third-party programs. • Automating the CLI with basic Bash scripting. Jo_o Marcelo Pereira Alves 10 ICB5765 4 The course is structured in short lectures intermingled with class activity sessions, in order to make the course as practice-oriented as possible. In order to better reflect everyday research practice, the most widespread file formats used in the field will also be introduced and used in as many practical examples as possible. The whole course, including exams, takes place in a computer lab. The use of the command-line environment of Unix-like operating systems (such as Mac OS X and Linux-based systems) will be intensively explored, in order to give students all the working knowledge necessary to run most bioinformatics tools and efficiently analyze their output. Avaliation Form: Final grade will be calculated as the weighted average of midterm exam (weight 2), final exam (weight 2), in-class quizzes (weight 1), and practical exercises (weight 3). A passing grade consists of 5.0 or higher final average and at least 75% attendance. Students with regular semester final grades between 3.0 and 4.9 and attendance above 75% can take a supplementary exam, in which case the second final grade will be the average of the final grade above and the supplementary exam. https://ww2.icb.usp.br/ing/

This course aims to teach techniques dealing with recombinant DNA and enable the students to perform a number of basic methodologies frequently used in laboratories which research activities in gene expression, molecular cloning and manipulation of DNA and RNA in general. Another goal is to complement informations given in other regular lessons and transmit a global vision to the student. The course is supposed to give postgrad students the opprotunity to acquire knowledge about Plasmodium and apply moleculares techniques. Further, by applying practical techniques, they learn different aspects about Plasmodium biology and malaria disease. In addition, the students Will have the opportunity to present general topics related to malaria in a series of seminars held in English or Portuguese language. Biomedical Sciences Institute (ICB) São Paulo main campus 1) Cloning of different genes encoding antigens of Plasmodium falciparum; 2) Purification of recombinant proteins by affinity chromatography. 3) PCR; 4) SDS-PAGE; 5) Western blotting; 6) ELISA 7) Real time PCR 8) DNA edition soiftare (ApE). The complete methods are provided in a manual which is delivered in the beginning of the course. Gerhard Wunderlich, Carsten Wrenger 2 BMP5785 5 The course is mainly meant for undergrad students in the last semesters of Biology, Biomedicine or Pharmaceutical Sciences. In case that the offered seats are not occupied by undergrad students, the remaining slots can be distributed among interested postgrad students. Before the course, all selected students meet with the professor in order to organize working groups of two students and distribute seminar themes. The course is mainly meant for undergrad students in the last semesters of Biology, Biomedicine or Pharmaceutical Sciences. In case that the offered seats are not occupied by undergrad students, the remaining slots can be distributed among interested postgrad students. Written exam and seminar presentations. https://ww2.icb.usp.br/ing/

Phycology is a broad area that studying a wide diversity of life forms, from prokaryotic organisms (cyanobacteria) to different lineages of eukaryotes. The knowledge about biodiversity, biology and biotechnological applications have advanced intensively in recent years in Brazil and abroad. Therefore, the focus of this course is to keep the graduate students aware of these advances, and promote presentations and discussions of diverse phycological topics in English. 1. Present and discuss phycological topics and related areas in order to provide a broad and updated knowledge to the students. 2. Expose research projects and seminars for discussion and suggestions, enabling the exchange of information between the projects developed by the students. 3. Offer the student an environment for training oral presentations and scientific debates in English. Institute of Biosciences (IB) São Paulo main campus Diverse and current themes on Phycology and related areas, including classical and molecular taxonomy and systematics, biogeography and phylogeny, ecology, physiology, chemistry, genetics, omics sciences, mariculture, environmental education and biotechnological applications of algae. The course will be based on oral presentation of seminars and discussions. Mariana Cabral de Oliveira, Fanly Fungyi Chow Ho 20 BIB5755 2 All students should present at least one seminar in English (including the oral presentation and slides) based on their research project or a related subject. http://www.ib.usp.br/en/

Integrate concepts from different areas of plant biology and update about the last generation experimental approaches Improve the knowledge about current topics, experimental approaches and techniques in plant biology Institute of Biosciences (IB) São Paulo main campus The subject will approach theoretical topics about gene expression regulation, genetic transformation, molecular markers, genomics, genetic and metabolic engineering, as long as technical aspects. The content will be introduced from the system biology point of view in an integrative and interdisciplinary manner, aiming the understanding of physiological and breeding processes Marie Anne van Sluys, Maria Magdalena Rossi 20 BIB5764 8 Class participation, lectures and tests http://www.ib.usp.br/en/

This is a class integrates the concepts of structural biology and bioinformatics. The basic principle of amino acids and structre will be explained first, then the modern methods to resolve atomic resolution of protein structures. The relation of protein structure and function will be emphasized in the third part of this class. Bioinformatic principles, methods and modern developments will be followed. 1. Understand amino acids and protein structures. 2. Modern approaches to resolve protein structure. 3. Protein structure and function. 4. Software-based analysis of protein sequence. 5. Bioinformatic theories 6. Current developments of bioinformatics methods. College of Life Science This class will be taught in English. CHII-SHEN YANG Friday 678 Biot8003 3 The upper limit of the number of non-majors: 15.

INTRODUCTION?EPIGENETIC OVERVIEW DNA METHYLATION AND GENOME DEFENSE RNAI AND HETEROCHROMATIN EVOLUTION OF MAMMALIAN EPIGENETIC CONTROL SYSTEMS EPIGENETICS AND DEVELOPMENT EPIGENTICS AND HUMAN DISEASE X-INACTIVATION GENOMIC IMPRINTING IN MAMMALS GENOMIC IMPRINTING IN PLANTS EPIGNETICS AND REPROGRAMMING EPIGENETICS IN ASSISTED REPRODUCTIVE TECHNIQUES APPLIED EPIGENETICS: FLOWERING PLANTS AND TISSUE ENGINEERING College of Bio-Resources & Agriculture Monday 678 Biot8001 3 The upper limit of the number of non-majors: 15.

This course examines the basic mechanisms of mechanotransduction and how it affects modulates cell and tissue behaviors. Applications utilizing physical stimulation will also be discussed. JOURNAL ARTICLES AND STUDENT PRESENTATIONS 1. Introduction – Cell Biology 2. Basics in Cell Signaling 3. Tension 4. Compression 5. Flow 6. Electric Fields 7. Osmotic Pressure 8. Intrinsic Cell Forces College of Engineering Class presentation of journal review and written as well as oral presentation of final project proposal. PENHSIU CHAO Biomed7002 1

1. INTRODUCTION 2. PROMISES OF STEM CELL RESEARCH 3. DEVELOPMENTAL CELL BIOLOGY 4. EMBRYONIC STEM CELLS 5. THERAPEUTIC CLONING 6. PLASTICITY OF STEM CELLS 7. STEM CELL HOMING AND ENGRAFTMENT 8. STEM CELL FATE: INTRINSIC AND EXTRINSIC FACTORS 9. STEM CELLS AND CANCERS 10. HEMATOPOIETIC STEM CELLS 11. MESENCHYMAL STEM CELLS 12. NEURONAL STEM CELLS 13. LIVER STEM CELLS 14. CORNEAL STEM CELLS College of Bio-Resources & Agriculture Thursday 678 Biot8002 3 The upper limit of the number of non-majors: 20.

This is a class integrates the concepts of structural biology and bioinformatics. The basic principle of amino acids and structre will be explained first, then the modern methods to resolve atomic resolution of protein structures. The relation of protein structure and function will be emphasized in the third part of this class. Bioinformatic principles, methods and modern developments will be followed. 1. Understand amino acids and protein structures. 2. Modern approaches to resolve protein structure. 3. Protein structure and function. 4. Software-based analysis of protein sequence. 5. Bioinformatic theories 6. Current developments of bioinformatics methods. College of Bio-Resources & Agriculture This class will be taught in English. CHII-SHEN YANG Friday 678 Biot8003 3 The upper limit of the number of non-majors: 15.