課程名稱: 細胞微機電及微流體導論 (Introduction to Cellular BioMEMS and Biomicrofluidics) 1.Cellular biomechanics: anatomy and physiology of cells, mechanics of cytoskeleton, cell-matrix interaction, focal adhesions, mechanical model, mechanoreceptors, mechanical behavior of cells: mitosis, migration, and introduction to infection induced cell abnormality. 2.Tissue Engineering: microcirculation, capillary anatomy, diffusion and convection, Starling law, osmotic pressure, interstitial flow, basics of angiogenesis and vasculogenesis. 3.BioMEMS: Photolithography, bulk micromachining, surface micromachining, micro-molding, plastic manufacturing. 4.Microfluidics: scaling laws, surface to volume ratio, hydraulic resistance, wall shear stress, diffusion, capillary flow, hydrodynamics in porous media. 5.Special topic: Cell-based chip for biotechnology – bioreactors, studies of mechanics of abnormal cells, cell sorting, cell trapping. 6.Special topic: BioMEMS for cell biology – substrate dependency of cells, cell-cell contact, cell migration. 7.Special topic: Tissue microengineering – 3D culture, angiogenesis, vasculogenesis, organ on a chip. (1) Introduce how to use basic mechanics to explain cell and tissue mechanics. (2) Explain how to apply cell mechanics to the design of BioMEMS and Biomicrofluidic devices (3) Understand the applications of BioMEMS and Biomicrofluidics in medical applications College of Engineering Main Campus Yu-Hsiang Hsu 20 Tuesday 7,8,9 AM7166 (543EM5310) 3 Non-degree Program: Nano-Technology Engineering,
(College of Engineering) Graduate Institute of Applied Mechanics http://www.iam.ntu.edu.tw/English/EN-homepage/homepage-Frameset.htm

Microelectromechanical Systems (MEMS) enable tiny devices or systems that can realize functions not easily achievable via transistor devices alone. This course focuses on the physical principles, tools, methodologies needed to properly model various types of MEMS sensors that are extensively used in our daily life. In addition, characterization of such MEMS sensors using open-source hardware will be covered through several hands-on laboratory sessions. College of Engineering Main Campus Experiments on Electronics Wei-Chang Li 16 Tuesday 7,8,9 AM7174 (543EM5370) 3 (College of Engineering) Graduate Institute of Applied Mechanics http://www.iam.ntu.edu.tw/English/EN-homepage/homepage-Frameset.htm

This course is to give an overview of circulatory biomechanics from the standpoints of engineering, physiology, and medical sciences. Experimental results from advanced clinical researches are used as examples and served as the guide to new focused research areas with great clinical values. Introduction to Physiological Fluid Dynamics Medical Terminology Physiological Properties of Human Body and Blood Rheology Dynamics of Circulatory System Relation of Cardiovascular Diseases (CVD) to Fluid Dynamics Mechanics of the Heart Principles of Ultrasound for BioFluid Research (Experiment 1) Arterial Fluid Dynamics and Hemodynamics(Experiment 2) Mechanical Properties of Arterial Vessels
(Experiment 3) Venous Fluid Dynamics Fluid Dynamics of Micro-circulation (Experiment 4) Fluid Dynamics of Pulmonary circulation Artificial Organs (Experiment 5) Grades: Literature reviews (Reports *3: 50%) Lab. Results & Discussion (*5; 50%) Text Book & References: 1. Biomechanics: Circulation (text book) by Y.C. Fung (Springer) 2. Biomedical Engineering Principles by David Cooney (Marcel Decker) 3. Biomechanics: Motion, Flow, Stress and Growth by Y.C. Fung 4. Blood Flow through Organs and Tissues by Bain and Harper 5. Cardiovascular Fluid Dynamics by Huang and Normann College of Engineering Main Campus Yio Wha Shau 20 Wednesday A,B,C AM7102 (543EM6230) 3 (College of Engineering) Graduate Institute of Applied Mechanics http://www.iam.ntu.edu.tw/English/EN-homepage/homepage-Frameset.htm

Course Syllabus: This design studio aims to bring the operation of spatial scenario into the field/work of the real world, and further amplify the analyses of social characters, landscape textures, and local narratives to construct a design methodology that is based on the site-specific and community-oriented mode of placemaking. The field operation is focused either on Taipei’s Shezi Island or Gah-lah, and the students will decide the location(s) of design intervention after individual and group visits. The possible sites include: 1. Li-zhongji courtyard house, Fu-zhou Settlement, Shezi Island 2. The route along the Waterfront Houseboat-Mouth of the Theater, His-zhou-di Settlement 3. The route along the embankment wall bike trail ramp-Li He-hsing House, His-sha-wei Settlement 4. Wanhe Garden, Fuzhou Settlement The Gah-lah site of Taipei’s south Wanhua District will be an in-situ transformation of a former dormitory bungalow interior into a shared community space. 5. Institution zoning #9 bungalow house The operation in either of the two fields is grounded on the spatial and social foundations established from previous practicum studios, and may involve hands-on construction. The design attitude of this studio is akin to the value revealed in the book title and case studies of Design Like You Give a Damn, and can be regarded as an intention of socially engaged design. Field/work is a learning site, and design is a process of spatial action. We will also appropriate the dialectics of ‘space of representation’ and ‘representation of space’ by Henri Lefebvre as the inception of understanding the field. But the building mode of the ordinary, or self-built/illegal buildings in Shezi Island or Gah-lah is rather different from the architectural production under the modernistic contract. The buildings are not necessarily constructed following the patent ‘representation’ (or architectural drawings, models, or 3D simulations), and the typology and meaning of their spatial symbols need to be researched and surveyed to become local knowledge. To ‘register’ or record the existing building patterns and spatial structures of the field can be regarded as a reverse typifying of ‘representation of space,’ that is, the ‘spaces of representation’ produced by ordinary people’s ‘spatial practices’ must be endowed with the source of meanings for the ‘representation of spaces’ so that we can extract the patterns, types, or critiques which the ensuing phases of the spatial production depend upon. When we systemize the representations of ordinary spatial practices, we may be able to construct a site-specific pattern language and develop the spatial scenario relevant to the design approach. This studio also encourages participant students to submit design proposals for New Taipei City’s ‘Social Housing for the Youth’ competition, and it will be further discussed through a collective decision making process. 1. learning the methodology of placemaking in design 2. hands-on practices and field researches of the real sites 3. collaborative design and community participation College of Engineering Main Campus 1. full participation and design practices 2. field works and representations 3. drawings, models, and presentations of different design phases 15 Tuesday A,B,C,D Friday A,B,C,D BP5016 (544EU1790) 6 *Registration eligibility: juniors and above.

(College of Engineering) Graduate Institute of Building & Planning http://en.bp.ntu.edu.tw/

This course will cover topics in particle technology, with an emphasis on the design and modeling of equipment for particle manufacture, separation and handling. We discuss the crystalline state of matter, crystal size distributions, crystal nucleation and growth, design of crystallizers and filters, fluidization, slurry transport, particle mixing and segregation, and particle size reduction and enlargement. Students will work in small groups to complete a design project. Several homework assignments will be given over the course of the semester. Exams will be open-notes. Grades will be determined approximately as follows: Homework 20% Semester Project 30% Mid-term exam 20% Final exam 30% References: Introduction to particle technology (2nd ed.) by Martin Rhodes Industrial crystallization : fundamentals and applications by Alison Emslie Lewis, Marcelo Martins Seckler, Herman Kramer and Gerda Van Rosmalen Crystallization : Basic Concepts and Industrial Applications. Edited by Wolfgang Beckmann College of Engineering Main Campus This class is suitable for senior undergraduate or graduate students in chemical engineering or a related field. Jeffrey Daniel Ward 50 Monday 7 Wednesday 8,9 ChemE5057 (524EU0210) 3 (College of Engineering) Graduate Institute of Chemical Engineering,
(College of Engineering) Department of Chemical Engineering http://www.che.ntu.edu.tw/che/?lang=en

1. Overview on Organic Functional Materials for Chemical Industry.(2 hr) 2. Functional Polymer Synthesis (6 hr) (1) Controlled polymerization using organocatalyst (2) Group transfer polymerization of methacrylate and acrylate (3) Ring-opening polymerization of epoxide (4) Ring-opening polymerization of cyclic ester and carbonate 3. Architecture and Morphology Control of Organic Materials (6 hr) (1) Synthesis of architecturally complex polymers (2) Synthesis of branched polymers (3) Synthesis of cyclic polymers (4) Phase separation and self-assembly of architecturally complex polymers 4. Electronic Device Applications (4 hr) II. Prerequisites: Organic Chemistry or Polymer Chemistry III. Grading Policy: Term paper or written exam. IV. Lecture Notes (ppt viewgraphs) will be provided but no textbook. Let the student understand the recent advances of polymer synthesis and applications. College of Engineering Main Campus Prerequisites: Organic Chemistry or Polymer Chemistry Wen Chang Chen 20 Thursday A,B,C ChemE5056 (524EU0650) 1 (College of Engineering) Graduate Institute of Chemical Engineering,
(College of Engineering) Department of Chemical Engineering http://www.che.ntu.edu.tw/che/?lang=en

I. Outline 1. Fundamental and Applications of Polycondensation (12 hr): Mitsuru Ueda 3/1 (6:30-9:20 pm), 3/2 (2:20-5:20 pm), 3/8 (2:20-5:20 pm), and 3/9 (6:30-9:20 pm) (1) Polycondensation, Polyaddition, and Poly)addition-condensation) (Review) (2) Control of Molecular Weight Distribution: Synthesis of Condensation Polymers with a Narrow Molecular Weight Distribution (3) C-H Activation: Metal Catalyzed Direct C-H Arylation for Synthesis of π-conjugated polymers (4) Sequence Control: Multicomponent Polymerization (MCP) (5) Regioselective Coupling: Oxidative Coupling Polymerization (6) Control of Branching: Synthesis of a Hyperbranched Polymer with Controlled Degree of Branching 2. Functional Polymers: Their Design and Synthesis (12 hr): Toshio Masuda 3/15 (2:20-5:20 pm), 3/16 (6:30-9:20 pm), 3/22 (2:20-5:20 pm), and 3/23 (6:30-9:20 pm) (1) Overview and Recent Progresses (2) Olefin Polymerization (3) Olefin Metathesis and ROMP (4) Various Conjugated Polymers (5) Polyacetylene (6) Substituted Polyacetylenes 3. Molecular Design and Precise Synthesis for Architectural Polymers (12 hr): Akira Hirao 4/6 (6:30-9:20 pm), 4/7 (6:30-9:20 pm), 4/12 (2:20-5:20 pm), and 4/13 (6:30-9:20 pm) (1) Polymer Blends and Multiphase Polymers (2) Block Copolymers from Living Anionic Polymerization (3) Precise Synthesis for Architectural Polymers from Living Anionic Polymerization 4. 4/19 break 5. 4/26 Midterm exam 6. 5/3 break 7. Conjugated Polymers: Fundamentals and Applications (18 hr): Wen-Chang Chen 5/10, 5/17, 5/24, 5/31, 6/7, 6/14 all from 2:20-5:20 pm (1) Design, Synthesis, and Properties of Conjugated Polymers (2) Conjugated Polymers for Light-Emitting Diodes (3) Conjugated Polymers for Field Effect Transistors (4) Conjugated Polymers for Photovoltaic cells. (5) Organic Electrical Memory Materials and Devices (6) Conjugated Polymers for Stretchable Electronics 8. 6/21 Final Exam II. Prerequisites: Organic Chemistry or Polymer Chemistry. III. Grading Policy: Term paper or written exam. IV. Lecture Notes (ppt viewgraphs) will be provided but no textbook. College of Engineering Main Campus Prerequisites: Organic Chemistry or Polymer Chemistry Wen Chang Chen 50 Wednesday 7,8,9 ChemE5058 (524EU0910) 3 (College of Engineering) Department of Chemical Engineering,
(College of Engineering) Graduate Institute of Chemical Engineering http://www.che.ntu.edu.tw/che/?lang=en

In this course we will cover the modern perspective of magnetism and magnetic materials. The lecture will start from the basics of electromagnetism and quantum mechanics, then go deeper into the concepts of quantum spin, spin-orbit interaction, and exchange interaction…etc. After understanding these basic principles, we will discuss the origins of various types of magnetic properties in different materials as well as the characterization techniques for obtaining these properties. For the last part, we will discuss the modern approach of combining electronics and magnetism into one big spintronics picture. We will go over some remarkable discoveries such as Giant magnetoresistance (GMR) and spin transfer torque (STT), which revolutionized the contemporary magnetic-memory development. I. Electromagnetism in a nutshell II. Quantum mechanics in a nutshell III. Magnetism in materials IV. Characterization techniques V. Transport measurements VI. Spintronics: Modern magnetism College of Engineering Main Campus General physics, Introduction to materials science and engineering Chi-Feng Pai 30 Wednesday 2,3,4 MSE7025 (527EM1690) 3 (College of Engineering) Graduate Institute of Materials Science and Engineering
http://www.mse.ntu.edu.tw/index.php?lang=en

The objective of this course is to explore the applications of biotechnology in environmental monitoring, environmental risk assessment, and remediation. The contents will cover microbial metabolic reactions, biodegradation of pollutants, and engineering applications in water, soil, and groundwater treatments. 1. Basics of microbial metabolism and ecology 2. Microbial degradation kinetics 3. Aerobic and anaerobic transformation 4. Biofilms 5. Bioremediation (soil and groundwater) 6. Phytoremediation 7. Biotechnology in wastewater treatment (aerobic and anaerobic) 8. Bioenergy recovery (from waste to energy) 9. Biotechnology in water treatment College of Engineering Main Campus Environmental microbiology Hsin-Shin Tung 20 Monday 7,8,9 EnvE8017 (541ED1150) 3 (College of Engineering) Graduate Institute of Environmental Engineering http://enve.ntu.edu.tw/dispPageBox/giee/GieeENHP.aspx?ddsPageID=GIEEEN

The course has the following major components: 1. Water uses and pollution: Overview of water characteristics, water uses, water pollutants; sources of water pollution, characteristics of domestic wastewater and industrial wastewater 2. Chemical reaction and pollutant transfer: Reaction kinetics, reaction equilibrium, mass balance, reactor performance, pollutant transport model 3. Water Quality in Natural Systems: Analysis of Lake eutrophication, conventional pollutants in rivers, etc.. 4. Water Pollution Management: Water quality monitoring, pollution management practices 1. Understand fundamental principles of water quality management 2. Use mathematical models to deal with water quality problems in natural and engineered systems. These include mass balance, reaction kinetics, and transfer mechanisms 3. Equip the knowledge to analyze the problems associated with water quality to predict impacts associated with the pollution of the environment College of Engineering Main Campus This course is taught in English Yi-Pin Lin 30 Tuesday 7,8,9 EnvE7073 (541EM0720) 3 (College of Engineering) Graduate Institute of Environmental Engineering http://enve.ntu.edu.tw/dispPageBox/giee/GieeENHP.aspx?ddsPageID=GIEEEN

This is the first course in numerical analysis for graduate students. The main objectives of this course include: (1) development and applications of numerical methods when analytical techniques are not available; (2) development of a conceptual framework for analysis of methods to fix the problem; (3) discrete calculus and approximations; (4) tradeoffs between accuracy and computational cost; 1. Interpolation (3 hrs)
(1) Lagrange Polynomials
(2) Polynomial Interpolations; Splines
2. Numerical Differentiation (4 hrs)
(1) Construction of Finite Difference Scheme, Order of Accuracy
(2) Modified Wavenumber as a Measure of Accuracy
(3) Pade Approximation
(4) Matrix Representation of Finite Difference Schemes
3. Numerical Integration (8 hrs)
(1) Trapezoidal Rule; Simpson’S Rule; Error Analysis and Mid-Point Rule
(2) Romberg Integration and Richardson’S Extrapolation
(3) Adaptive Quadrature; Gauss Quadrature
4. Numerical Solution of Ordinary Differential Equations (10 hrs)
(1) Initial Value Problems; Numerical Stability Analysis, Model Equation
(2) Accuracy; Phase and Amplitude Errors
(3) Runge-Kutta Type Formulas, Multi-Step Methods; Implicit Methods
(4) System of Differential Equations; Stiffness
(5) Linearization For Implicit Solution of Non-Linear Differential Equations
(6) Boundary Value Problems, Shooting, Direct Methods, Non-Uniform Grids, Eigenvalue Problems
5. Partial Differential Equations (10 hrs)
(1) Finite-Difference Solution of Partial Differential Equations
(2) Modified Wavenumber and Von Neumann Stability Analysis, Modified Equations Analysis
(3) Alternating Direction Implicit Methods; Non-Linear Equations; Iterative Methods for Elliptic Pde’s College of Engineering Main Campus HOMEWORKS (55%); MIDTERM EXAM (%15); FINAL EXAM (%30) Chou, Yi-Ju 54 Tuesday 7,8,9 AM7008 (543EM1110) 3 (College of Engineering) Graduate Institute of Applied Mechanics
http://www.iam.ntu.edu.tw/English/EN-homepage/homepage-Frameset.htm

This course will discuss traveler behavior within and relative to transportation systems. One major focus is to read behavioral patterns from data using a variety of econometric tools and understand the relevant theories and mathematics. This course will also explore the cognitive process for travel decision-making at the level of psychological analysis, ultimately seeking to derive its implications in the planning, design and operation of a transportation system. College of Engineering Main Campus Assignment: 35% In-class participation: 15% Mid-term examination: 20% Term project: 30% Yu-Ting Hsu 20 Tuesday 2,3,4 CIE5104 (521EU8850) 3 (College of Engineering) Department of Civil Engineering,
(College of Engineering) Graduate Institute of Civil Engineering, Transporation Engineering Division
*Majors-only (including minor and double major students). http://www.ce.ntu.edu.tw/ce_eng/