Special Topics in Equine Reproduction

To discuss matters related to equine reproduction, not available in the regular courses offered by the Graduate Program in Animal Reproduction, with the participation of professors, researchers and professionals from other national and international institutions. To address current and relevant subjects in the field of equine reproduction, offering student the opportunity to engage in discussions and establish collaborations with professors, researchers and invited professionals. School of Veterinary Medicine and Animal Science (FMVZ) São Paulo main campus Program content addresses the field of equine reproduction, including reproductive physiology, management, pathology, biotechnology and obstetrics. This will more precisely defined by the visitor professor, researcher and professional expertise. Claudia Barbosa Fernandes 25 VRA5752 1 Participation concepts. http://ccint.fmvz.usp.br/index.php/en/

Fundamentals of Multimedia

Many society areas use computational applications in order to manipulate different media types, in a integrated fashion or not. The information volume generated by those applications and the need for inter-media synchronization make necessary to use coding techniques as well as standards to guarantee efficiency and interoperability. The knowledge about those techniques and standards are essential for graduated students develop research in the Multimedia area. The goal of this course is to present multimedia fundamentals, approaching important issues regarding different media types and coding methods. It is also in the scope to analyze features and limitations of available tools, applications and systems. After the course we expect the student to be capable to discuss recent related research topics. Institute of Mathematical and Computer Sciences (ICMC) São Carlos campus Mutimedia definition. Introduction to digitization. Compression of different media types. Basic compression techniques. Spatial and temporal coding.Standards. Multimedia segmentation and adaptation. Multimedia authoring. Maria da Gra_a Campos Pimentel, Rudinei Goularte, Marcelo Garcia Manzato 30 SCC5909 7 The final grade will be obtained calculating a weighted average among exams, projects and seminars. http://conteudo.icmc.usp.br/Portal/conteudo/1079/538/foreign-scholars

Human-computer Interaction I: Fundamentals

Interactive systems are present in the daily lives of individuals who make explicit or implicit use of a variety of computing devices. This course provides students with a comprehensive overview of the key concepts, techniques and methods that can be used in the design and evaluation of such systems. The course aims at presenting the fundamental concepts, techniques and methods for the design, development and evaluation of interactive systems. Institute of Mathematical and Computer Sciences (ICMC) São Carlos campus Interaction design. User experience. Conceptual models. Metaphors. Paradigms. Cognitive, social and emotional aspects. Interface types. Natural interfaces. Interfaces for mobile devices. Techniques for identification and analysis requirements. Design, prototyping and construction. Agile UX. Design patterns. Avalia__o: inspection techniques and usability testing. Maria da Gra_a Campos Pimentel 30 SCC5912 8 The complementary course “Human-computer Interaction II: practice” allows students to develop a project while applying the concepts tackled in this course. Weighted average among exams, seminars and practical work. http://conteudo.icmc.usp.br/Portal/conteudo/1079/538/foreign-scholars

Natural and Artificial Vision

The topics covered in this course are of great importance and modernity regarding both biological vision as well as image processing and artificial vision. The integrated approach uses parallels between biological and computational systems, which is seldom covered in graduate courses in Brazil. Familiarization with intermediate and advanced concepts in the areas of natural and artificial vision. With respect to natural vision, we cover the anatomic organization of the visual system is presented, its physiology (special attention given to receptive fields), as well as aspects of neuroscience and psychology of vision. Regarding artificial vision, we present correlated aspects such as visual information processing in linear and non-linear systems, curvature and thinning methods, as well as pattern recognition using supervised and non-supervised approaches. S_o Carlos Institute of Physics (IFSC) São Carlos campus Part I: natural vision systems. 1. primitive natural vision systems (insects, arthropods, molluscs, etc). 2. advanced natural vision systems (including respective mathematic-computational modelling) 2.1. neuronal processing, principles of formation and propagation of stimulii in neutrons, respective modeling. 2.2. basic processing, retinal processing, lateral geniculate nucleous, receptive fields, superior colliculus, motor control. 2.3. visual cortex processing (neurophysiology, types of cells, modular organization in bands an pinwheels, visual cortex modelling through Hough transform). 2.4. processing in higher level cerebral structures (memory, inference, language, attention), modelling multiple stage integration. Part II: artificial vision systems (including basic principles, algorithms and implementation in sequential and parallel hardware) 1. integration between natural and artificial vision 1.1. principles of cybernetics 1.2. D. Marr�fs proposal 1.3. geometric quantized elements 2. neuronal networks for pattern recognition 2.1. perceptrons 2.2. networks based on the Hough transform 3. signal processing techinques (basic level vision) 3.1. autocorrelation and convolution 3.2. filters 3.3. the two dimensional Fourier transform 3.4. wavelet transforms 4. mathematic-computationa techniques for intermediatee vision 4.1. mathematical morphology: Minkowski�fs algebra 4.2. the Hough transform 4.3. segmentation techniques 4.4. data structures for representation of visual information 4.5. estimation of tangent fields and multi scale curvature 4.6. multiscale skeletons 5. computational models for high level vision 5.1. object oriented systems 5.2. databases and knowledge 5.3. artificial intelligence models 5.4. automatic knowledge acquisition. Luciano da Fontoura Costa, Odemir Martinez Bruno 25 SFI5818 15 Two written and a substitutive written examinations. Several practical projects and seminars. https://www2.ifsc.usp.br/english/

Non-Abelian Gauge Theories and Solitons

It is very importante nowadays that theoretical and also experimental physicists have a reasonable knowledge about the field theories that describe the fundamental interactions of Nature. Those theories find applications in practically all areas of Physics. To give the students a solid education about the structure of abelian and non-abelian gauge theories that describe the fundamental interations of Nature, like Electrodynamics and the Weak and Strong nuclear interactions. S_o Carlos Institute of Physics (IFSC) São Carlos campus 1. Introduction to gauge theories 2. Non-abelian gauge theories 3. The self-dual sector – instantons 4. Spontaneous symmetry breaking 5. Goldstone’s theorem 6. Higgs Mechanism: little group and mass formulas 7. Classical solutions: Magnetic monopoles, dyons and vortices 8. Bogomolny equation and BPS monopoles 9. Solitons and electromagnetic duality 10. Supersymmetric gauge theories Luiz Agostinho Ferreira, Betti Hartman 20 SFI5876 10 Written tests and exercise lists. https://www2.ifsc.usp.br/english/

Riemannian Geometry

Riemannian Geometry is a basic course for any graduate student in Mathematics who wants to study Geometry, Topology or Dynamic Systems, and is also a relevant course for students of Analysis and Applied Mathematics. Provide to the student the basic tools and some fundamental results of Riemannian Geometry. Institute of Mathematical and Computer Sciences (ICMC) São Carlos campus Program: Riemannian metrics; Connections; Completeness; Curvature; Isometric immersions; Variational calculus; Applications. Detailed program: (1) Riemannian metrics; Examples of Riemannian manifolds: the Euclidean space R^n, the sphere S^n, the real hyperbolic space H^n, product of Riemannian manifolds, conformal metrics, Riemannian coverings, flat tori, the Klein bottle, Riemannian submersions, the Hopf fibration and the complex projective space, quotient manifolds, Lie groups. (2) Connections; Parallel transport along a curve; Geodesics; Isometries and Killings vector fields; Induced connections. (3) Completeness; The Hopf-Rinow theorem; Cut locus, Examples. (4) The Riemann-Christoffel curvature tensor; The Ricci tensor and scalar curvature; Covariant derivative of tensors; Examples. (5) Isometric immersions; The second fundamental form; The fundamental equations. (6) Variational calculus; The energy functional; Jacobi vector fields; Conjugate points; Examples. (7) Space forms; The Synge theorem; The Bonnet-Myers theorem; Nonpositively curved manifolds. Fernando Manfio, Irene Ignazia Onnis 35 SMA5947 8 Two written tests. http://conteudo.icmc.usp.br/Portal/conteudo/1079/538/foreign-scholars

Molecular Biology Applied to Animal Embryology Study Molecular Epidemiology and Genetics of Toxoplasma gondii using Multiplex PCR-RFLP and Whole Genome Sequence Analysis

The development of molecular biology revolutionized the way investigators conduct research. Techniques such as polymerase chain reaction, sequencing, gene knockdown and others became routine tools for researchers on molecular biology field. However, researchers from other areas may be not familiarized with such techniques. Considering the importance these techniques for science development is mandatory that the students from the graduate program in Anatomy have a minimal knowledge on molecular biology, allowing them to interpret publications with molecular data and to consider multiple approaches while developing their own research projects. Provide to graduate students: theoretical and practical concepts on molecular biology techniques, with emphasis on mammalian development applications; knowledge to interpret the results generated by molecular biology assays; a critical view of molecular biology techniques that can be used in scientific investigation, development of the necessary skills to use molecular biology and to critically analyze publications with molecular data. School of Veterinary Medicine and Animal Science (FMVZ) São Paulo main campus Essentials of molecular biology, nucleic acids extraction, polymerase chain reaction, restriction fragment length polymorphism, nucleic acid sequencing, real time PCR, high resolution melting, microarrays, genotyping, western blot, transgenesis and gene silencing. 25 VPS5745 4 Students will be assessed through participation in classes and the presentation of papers. http://ccint.fmvz.usp.br/index.php/en/

Endocrinological aspects of follicular development and ovulation

The knowledge within the animal reproduction context is new. Still, there are enormous possibilities to apply the reproductive biotechnologies using controlled follicular development and ovulation in the field. And it is noteworthy that the Department of Animal Reproduction has a line of research related to the theme which is coordinated by the professors who are proposing this course. Study in detail the endocrinological aspects of follicular development and ovulation empathizing the employment of the synchronization biotechnology for timed reproductive programs. The objective is also to develop in the graduate the capacity of critical analysis of issues related to the theme. School of Veterinary Medicine and Animal Science (FMVZ) São Paulo main campus 1- Physiology and endocrinology of follicular development; 2 – Follicular dynamics during reproductive life; 3 – Basics of ultrasound applied to follicular dynamics; 4 – Theories of the pharmacological control of the estrous cycle and ovulation; 5 – Hormone therapy; 6 – Anestrus; 7 _ Protocols to synchronize the follicular growth and ovulation; 8 – Possibilities to use the fixed-time artificial insemination in the field; 9 – Efficiency of the synchronization protocols for superovulation and fixed-time embryo transfer. Ed Hoffmann Madureira, Pietro Sampaio Baruselli 30 VRA5741 4 The evaluation is carried out at the end of the course with the presentation of seminars related to the content. http://ccint.fmvz.usp.br/index.php/en/

Writing your Manuscript

This course has the objective of teaching postgraduate students to become more effective writers, using practical examples and exercises. Topics include: principles of good writing, tricks for writing faster and with less anxiety, the format of a scientific manuscript, authorship, plagiarism. At the end, the students should delivery a short paper for peer review. This step is essential for the final evaluation. To learn about how to write an effective manuscript during the postgraduate course can help the students to report adequately your scientific results. Additionally, the program and the mentors could be benefited. Ribeir_o Preto Medical School (FMRP) Ribeirão Preto campus – Scientific project approved by Ethical Committee – Data explored/analyzed (at least partially) – Fluency in English – Personal computer (notebook) – operacional systems Linus, OS, Windows – Softwares installed: text editor (suggestion: Word_ or Pages_), reference manager (suggestion: Endnote_). – Introduction, the importance of a good writing divulgation – Good relationship with a text editor – Principles of effective writing – Crafting better sentences and paragraphs – Organization; and streamlining the writing process – The format of an original manuscript – Reviews, commentaries, and opinion pieces; and the publication process – Issues in scientific writing (plagiarism, authorship, ghostwriting, reproducible research) – How to do a peer review Om_ro Benedicto Poli N_tto 25 RGO5865 6 How much of a time commitment will this course be? – You should expect this course to require 4 to 8 hours of work per week. Any additional textbooks/software required? – There is no textbook for this course. PRESENCE: 91-100%: excellent, grade A; 81-90%: above average, grade B 71-80%: satisfactory, grade C; below 70%: unsatisfactory, grade D TASKS DELIVERED ON TIME*: All of them (5/5): excellent, grade A; 80% (4/5): above average, grade B 60% (3/5): satisfactory, grade C; below 40% (2/5): unsatisfactory, grade D * Tasks will be accepted only until to one week after. * If any task is not sent at this time (one week after), the grade will be decreased by “D” level. * Presence and tasks delivered on time will be compound as “Participation”: A+A=A; A+B=A; B+A=A;B+B=B; B+C=B; C+B=B; C+C=C; C+D=D; D+C=D; D+D=D. If D, the student will not be automatically reproved in the course. FINAL REPORT: graded from zero to ten by average grade among teacher and peer review (made by two colleagues). FINAL GRADE: It will be equal to �gFinal report�h x 100% if �gParticipation�h=A or 85% if �gParticipation”=B or 70% if �gParticipation�h=C. ATTENTION: Final grade will not be attributed if �gParticipation”=D. IMPORTANT: If any sign of plagiarism is detected, the student will have one additional week to sent a new version of the final work and will have the final grade decreased in 20%._ http://www.fmrp.usp.br/?lang=en

Immunotherapies and cellular therapies: concepts and applications

Currently, immunotherapy is an important therapeutic approach for the treatment of several diseases. In this context, this discipline is justified by addressing the current state and new perspectives of immunotherapies and advanced cellular therapies, making a connection between basic concepts and possible preclinical and clinical applications. Immunotherapy for cancer treatment is currently the most promising therapy in view of its selectivity, curative potential and low toxicity. This type of therapy has been described as the major scientific event of 2013 by the journal Science with emphasis on therapies with monoclonal antibodies (anti-CTLA-4 and anti-PD1) and genetically modified chimeric antigen receptor T cells (Chimeric Antigen Receptor T Cells, CAR T cells), which were able to induce potent antitumor response. In addition, this course enables interaction with professors and researchers from our and other research institutions, which develop works in this area of knowledge and present significant scientific and/or technological contribution in the field. The objective of this course is to introduce concepts about immunotherapies and cell therapies, as well as to discuss their application in the treatment of several types of diseases (hematological neoplasms, solid tumors, inflammatory diseases and immuno-mediated diseases.) In this context, immunotherapies already well established in the clinical context as well as innovative and advanced therapies using, for example, multipotent stem cells and genetically modified T cells. In addition, biotechnological advances in the areas of immunotherapy and cell therapy will be addressed. Ribeir_o Preto Medical School (FMRP) Ribeirão Preto campus The course will be taught through lectures, seminar presentation and discussion of articles. It will cover the following topics: 1. Immunotherapy, cell therapy, gene therapy: concepts and definitions. 2. Cellular immunotherapy (eg, NK cells, genetically modified T cells, dendritic cells, regulatory T cells, among others). 3. Immunotherapeutics (eg monoclonal antibodies, soluble receptors, receptor antagonists, purified total immunoglobulins, among others). 4. Immunotherapy: preclinical and clinical applications. 5. New biotechnologies in the area of immunotherapy (genetic modification, construction of chimeric antigen receptors, bioprocesses for cell expansion in bioreactors, humanized antibodies, among others). Maria Carolina de Oliveira Rodrigues,Kelen Cristina Ribeiro Malmegrim de Farias, Cristina Ribeiro de Barros Cardoso 25 RIM5754 4 There will also be the participation of invited researchers from this and other institutions every time the discipline is offered. 1) Didactic-scientific performance in seminars 2) Participation in discussions during lectures and seminars 3) Frequency http://www.fmrp.usp.br/?lang=en

Study of mother-infant interaction in an ethological approach: theoretical and practical aspects.

The initial mother-baby/infant is a subject of research interest of all areas in Psychology and its importance for the development of the infant and for the attachment bond is consensus among Ethologists. The ethological approach offers an important theoretical contributions to the study of these early exchanges and methodological contributions through methods of direct observation of different aspects of this relationship. In addition, learn to use modern tools, used by Behavioral researchers around the world, will be of great value to students with research interests centered on social relations, and specifically on the mother-baby/infant relationship. To present the ethological approach to study of the early mother-infant interactions, focusing on the contribution of researches with non-human primates and, in a broader perspective, compared to the maternal care in humans. The discipline will also have practical classes, in which the students will learn about methods of investigating the mother-infant interactions through direct observation, especially videotape data, ant to use modern software of video analysis (Observe XT) to quantify and measure diverse aspects of mother-infant interaction. It is expected that in the end of the course, students can be able to plan and conduct a research in this area. Institute of Psychology (IP) São Paulo main campus Mother-infant interactions in an ethological perspective: historical bases and contributions from comparative approach; Parental investment, maternal styles of care, attachment, and parent-offspring conflict; Mother-infant initial interactions and their implications for the attachment bound and infant’s development; Proximate and ultimate causes of variation in maternal care; Models of parental practices in humans; Methods of observation to investigate mother-infant interactions; Process of design and conducting investigation on social interactions though direct observation; Introduction to software tools to encode and measure observational data in video (Observer). Michele Pereira Verderane 22 PSE5942 8 Participation in class, oral presentation, and written report. http://www.ip.usp.br/psiclin/index.php?option=com_content&view=frontpage&lang=en