Plasma physics is used in modern technological applications, astrophysics and controlled thermonuclear fusion. In all these three topics, USP has research groups that could benefit from this course. Inicial formation in plasma physics for postgraduate students. Institute of Physics (IF) São Paulo main campus _Classical Mechanics and Electromagnetism (graduation level) 1. Basic concepts in plasma physics 2. Laboratory and astrophysical plasmas 3. Movement of charged particles in electromagnetic fields 4. Kinetic and fluid descriptions of magnetized plasmas 5. Magnetohydrodynamic equilibrium of tokamak plasmas 6. Waves in plasmas (fluid description) 7. Magnetohydrodynamic instabilities Gustavo Paganini Canal 50 PGF5112 12 Written exams and series of exercises. http://portal.if.usp.br/ifusp/en/welcome-ifusp

This discipline complement the study of evolution of dissipative dynamical systems presented during the graduation in Mechanics and other disciplines. The presented concepts and procedures are applied to non linear systems in classical physics and interdisciplinar science. Study the main chaotic dissipative systems in classical physics and their applications in interdisciplinary areas, applying the theory of chaos to characterize them. Reproduce numerical examples of the main results described in text books. Institute of Physics (IF) São Paulo main campus Graduation Chaotic trajectories in dynamical systems described by maps. Chaotic trajectories in dynamical systems described by differential equations. Fractals. Periodic, quase-periodic, and chaotic attractors. Linear stability. Routes to chaos: crisis, bifurcations, intermitency. Control of chaos. Ibere Luiz Caldas 40 PGF5202 12 Final grade determined by the average between grades from three numerical exercise lists and a seminar http://portal.if.usp.br/ifusp/en/welcome-ifusp

Considering that graduate courses aim to develop qualified faculty and researchers, able to conduct research protocols independently, it is necessary to offer disciplines which prepare students with adequate statistical tools for the analysis of collected data from health research protocols. At the end of this discipline students should be able to: 1. Recognize and classify research variables as well as understand the consequences of this classification on statistical analysis; 2. Present collected data in a reduced form applying tables and graphics; 3. Distinghish the most used probability distributions and relate them to their respective statistical tests; 4. Define Type I and Type II errors, and how they are related to the sample size; 5. Indicate apropriate statistical tests to run univariate and bivariate hypothesis tests; 6. Interpret results of univariate and bivariate statistical analysis. Medical School (FM) São Paulo, Pinheiros campus 1. Descriptive Statistics: variables; reducing and presenting data (graphs and tables); frequencies; central tendency measures and dispersion. 2. Introduction to Probability: axioms; dependent e independente events; conditional probability; Probability distribution: Binomial, Poisson, Normal, F, t e _2; 3. Inferential statistics: hypothesis testing; type I and type II errors. Confidence interval; z test. Sample size calculation and study power. 4. Tests for quantitative variables: t test; paired t teste; F test; ANOVA, Pearson correlation. 5. Tests for ordinal variables: Mann-Whitney test; Wilcoxon test; Kruskal-Wallis test; Spearman correlation. 6. Tests for categorical variables: _2 test; Exact Fisher test; Relative Risk; Odds Ratio; Cochran-Mantel-Haenszel method. Luiz Felipe Pinho Moreira, Raymundo Soares de Azevedo Neto 30 MPT5802 2 This discipline is offered at the School of Medicine main building as well as in a distance learning format. In the distance learning format, students will watch classes and discuss the topics through MOODLE platform (Stoa _ http://stoa.usp.br ). Final exam is performed at the School of Medicine. A final exam, with multiple choice questions, will be carry out at the end of the discipline, being necessary a score higher than 50 of 100 points for the student to get approved. http://www.fm.usp.br/en/portal/

This course covers the current knowledge on the molecular and cellular mechanisms involved in the control of hematopoiesis and hematopoietic defects that are etiologic in human hematologic disorders Discussing the cell and molecular mechanisms of control of hematopoiesis, maintenance of pluripotency and hematopoietic stem cell differentiation. Discussing the mechanisms regulating hematopoiesis which are abnormal in hematological diseases, particularly in bone marrow failure and myeloid neoplasias. Ribeir_o Preto Medical School (FMRP) Ribeir_o Preto campus Lectures on (1) hematopoiesis and (2) bone marrow failure. Seminars on pluripotency, stemness, hematopoietic differentiation, cellular reprogramming; immunology of hematopoiesis, niche; DNA repair machinery, telomere biology, clonality in hematopoieses, malignant clonal evelution, epigenetics, and investigational tools: Southern blot, Westem blot, coimmunoprecipitation, qPCR, PCR-array, genetic sequencing, colony-forming assays; immunophenotyping Rodrigo do Tocantins Calado de Saloma Rodrigues 4 OCT5717 4 The discipline is held in a weekly basis and students’ evaluation will be based on: 1. Frequency and participation; 2. Seminars presentation; 3. Top http://www.fmrp.usp.br/?lang=en

Over the last few years, USP graduate students have increased their participation at overseas conferences or events in Dentistry. These events require students to write abstracts and give presentations in English. Besides, students need to be equipped with the language skills necessary for writing papers. Foreign students enrolled in Dentistry courses need English-medium lectures. ENGLISH FOR ACADEMIC WRITING The course will focus on: • Raising awareness of the main issues in English writing. • Discussing issues related to translation. • Building up vocabulary and phrases used in an academic environment. • Revising some of the most difficult points of grammar and learning more features of English grammar appropriate to an academic environment. • Providing hands-on practice for students in writing. • Improving student’s editing skills. • Getting familiar with online dictionaries and corpora. 2) ENGLISH FOR ACADEMIC PRESENTATIONS The course will focus on: • Building students’ oral communication skills. • Developing oral grammatical accuracy and range of structures. • Learning useful phrases in presentations. • Improving pronunciation. • Contrasting English and Portuguese phonological traits. • Giving presentations. • Analyzing participant’s presentations collaboratively. School of Dentistry (FO) São Paulo main campus 1. Lexical study 2. Study and revision of grammatical structures 3. Text writing 4. Pronunciation study 5. Oral presentation Marina Helena Cury Gallottini, Marcelo Jose Strazzeri Bonecker, Patricia Moreira de Freitas Costa e Silva 15 ODO5785 4 Presence, critical participation, oral presentation and written works. http://www.fo.usp.br/?lang=en

A deep knowledge of Quantum Mechanics is paramount for every physicist. Advanced topics not covered in PGF5001, develop familiarity with the ideas and methods of Quantum Mechanics and study applications to physical systems. Institute of Physics (IF) São Paulo main campus Quantum Mechanics I (PGF5001). WKB approximation, Variational methods, Time-dependent perturbation theory, Identical particles, Scattering theory, S-matrix, Eikonal approximation, Interaction radiation/matter, Canonical formalism, Path integrals, Symmetries and conservation laws, Particles in e/m fields, Entanglement, Interpretations of Quantum Mechanics, Basics of quantum computation. Oscar Jose Pinto Eboli, Matthew Wiiliam Luzum, Enrico Bertuzzo 50 PGF5002 12 Homeworks and exams http://portal.if.usp.br/ifusp/en/welcome-ifusp

Quantum Field Theory is a tool of critical importance in several areas including high energy physics and condensed matter physics. Students doing research in these areas would benefit greatly from the content of this course. To provide students with the basic elements of Quantum Field Theory that would allow them to use this important tool in their research. Institute of Physics (IF) São Paulo main campus Introduction to Quantum Mechanics. Introduction. Classical Theory of Fields. The need for Quantum Field Theory. Path integral in Quantum Mechanics. Functional methods and quantization of scalar theories. Functional integral for fermion fields. Aplications: relativistic and statistical (many body) systems. Interactions and perturbation theory. S matrix and cross sections. Quantization of gauge fields. Quantum electrodynamics. Renormalization and regularization. Renormalization group. Gustavo Alberto Burdman 40 PGF5107 12 Homework, final project. http://portal.if.usp.br/ifusp/en/welcome-ifusp

The subject, besides fulfilling the primary aim of the “gstrictu senso”h post-graduation of training researchers, combines the need for stimulation, starting at a brilliant idea (the Concept of Intellectual Capital, where the knowledge or creativity can be converted into economic value) up to the development of products, and their branding and patenting. To present the postgraduate students the understanding, skills and attitudes which must be developed to enable getting a brand and patent, from the conception of an idea – To stimulate the creativity of the postgraduate student in the creation of innovative products, which could become innovations with their institutional domain guaranteed. Medical School (FM) São Paulo, Pinheiros campus Define what intellectual property is, and identify its importance for Brazilian industry Since when have people sought to protect intellectual property? What is intellectual property? What does intellectual property cover? Current regulationary framework that deals with intellectual property in Brazil Conceptualize about what copyright and related rights are and their implications What guarantees copyright in Brazil? Copyright Related rights Explain what the rights are over a computer program Computer Program Identify what industrial property is and its applications: patents of invention and utility model, trade mark, industrial design and geographical indications. Who guarantees and grants the right of industrial property in Brazil? What does the expression industrial property cover? What is the purpose of industrial property Patent of Invention and Utility Model Industrial Design Registration Trademark Registration Registration of Geographical Indications Repression of Unfair Competition Current regulatory framework to support innovation in Brazil Having ideas in Gastroenterolgy (a. innovation which could be patented; b. methods for scientifically developing an idea; c. putting the project into practice. – Idea Development Projects, trademarks and patents in Endoscopy and Interventional Radiology – Idea Development Projects, trademarks and patents in Surgery. Orlando de Castro e Silva J_nior, Eduardo Guimar_es Hourneaux de Moura, Wanderley Marques Bernardo 34 MGT5773 4 Concepts which involve the proposed subject: – Idea: The word derives from the Greek idea or eidea, etiological root is eidos _ image. Its significance, since its origin, implies a controversy between the theory of emission (Plato) and that of intromission (Aristotle). At the center of the controversy is the concept of the representation of the real (reality). For Plato, the idea we have from something proves the main principal, of the _intelligible world_, which constituted the Universal Idea, a category which is the basis of his philosophy, idealism. So, the idea of it is a projection of knowledge: upon seeing it, the eyes, emitting rays of light, project the image of the same thing, which exists within us as the universal principle (emission). This doctrine is designed by _idealism_. For Aristotle, the idea of the thing comes from sense experience, from the _world of contingent phenomena_: the things emit copies of themselves, through the light, copies assimilated by senses and interpretated by innate or acquired knowledge (intromission), a doctrine that founds the concept of _realism_. The (brilliant) idea is the basis of everything (four steps: preparation, incubation, illumination and verification). Any time lost after a brilliant idea could be responsible for inhibiting the motivation which created idea, or even raise doubts whether the brilliant idea is really good or not. – Intellectual property: refers, in the broad sense, to the creations of human spirit and to the protective rights of the interests of the creators over their creations. – Trademark: Is a visually perceptible sign capable of distinguishing the goods or services of a company, especially in relation to other competitors. – Patent: is a title of temporary ownership over an invention of utility model, granted by the State. With this right, the inventor has the right to prevent third-parties, without their consent, of producing, using, putting for sale, selling or importing the subject of their patent and/or process or product obtained directly by a process patented by him. _Assessment by: above 75% presence in lesson, presentation of seminars with pre-determined topics, performance and interest demonstrated during the discussions. http://www.fm.usp.br/en/portal/

Despite unprecedented efforts to control malaria, this disease still represents a major public health problem, particularly in Africa. Challenges such as the search for more sensitive point-of-care methods, resistance to antimalarials and to insecticides, strategies to measure transmission, understanding of the immunity and decreases lethality are challenges for the control and elimination. Malaria is the most widespread parasitic disease, putting at risk about 3.3 billion people worldwide, with 198 million cases and 584,000 deaths, especially in children under five years of age and pregnant women. Leishmaniasis and arboviruses such as dengue are among the vector-borne diseases considered neglected by the World Health Organization. Neglected tropical diseases are a group of communicable diseases occrurring in tropical and subtropical conditions in 149 countries and affect more than one billion people, at the cost of billions of dollars each year. They affect mainly populations that live in poverty, in contact with vectors of infectious agents. About 450 million people in sub-Saharan Africa are at risk of contracting tropical diseases. However, according to the WHO, they also affect Latin America, the Middle East and Asia and can emerge in other regions. Leishmaniasis accounts for 1.5 to 2 million new cases per year, with an average lethality of 7%, mainly due to the visceral type. In recent years there has been a resurgence of different arboviruses, among them dengue, chikungunya and Zika virus, whose ability to adapt to different vectors had an impact on the geographical expansion of these diseases. Although most cases present benignly, these arboviruses can occur with severe manifestations. The risk of transmission of these diseases is not limited to populations living in areas at risk, but also to travelers, due to globalization and ease of displacement, thus increasing the concern of worldwide dissemination. The extent of these diseases, coupled with the complex mechanisms of the agent-host-vector relationship in the different phases of the transmission chain, suggests that it is appropriate for academic and public health institutions to devote themselves to the study of the variables involved in their evolution. Thus, the knowledge related to the agents, the hosts, the vectors and the interaction between them, is fundamental to draw efficient strategies of control. In this context, the main challenges are the critical and accurate evaluation of parasitological and molecular diagnostic methods; the immunological mechanisms involved in the etiologic agent-man-vector relationship; the genetic mechanisms of drug resistance; the importance of travel medicine, in order to guide and prevent the risk of infection. It is proposed here a course at a postgraduate level that will provide students with the conditions to develop a critical vision, that arises from the knowledge of challenges, proposals for control and research perspectives in the related field. Training teachers and researchers to develop research on malaria and the main neglected tropical diseases, with an approach in epidemiology and clinical-laboratory diagnosis, encouraging and stimulating the critical thinking related to the knowledge in these diseases. Medical School (FM) São Paulo, Pinheiros campus 1. Challenges for malaria control: biological, epidemiological and environmental components; dynamics of transmission in different endemicities; determinants of malaria; characteristics of extra-Amazonian malaria; 2. New perspectives in laboratory diagnosis of malaria: performance of molecular protocols and adequacy of their use in different situations; critical analysis of immunochromatographic assays for the detection of specific antigens and antibodies; 3. Development of immunity in malaria: main mechanisms involved in the cellular and humoral immune response; current state of vaccine development; 4. Immunopathogenic aspects of malaria and correlation with clinical manifestations: characteristics of severe malaria; 5. Chemotherapy; genetics of antimalarial resistance and major molecular markers; 6. Challenges for the control of leishmaniasis: determinants of the disease endemicity, mechanisms related to environmental factors contributing to the spread of the disease; 7. Diversity of Leishmania species occurring in Brazil: geographical location; clinical forms of disease; species and genotypes of Leishmania-related therapeutic response; 8. Innate and adaptive immunity in leishmaniasis: immunopathogenic aspects of the different clinical forms of tegumentary and visceral leishmaniasis; 9. Clinical-laboratory diagnosis of leishmaniasis; clinical aspects in immunocompetent and co-infected patients with HIV; difference in clinical manifestations and therapeutic response; evaluation of laboratory methods currently employed in the diagnosis of visceral and tegumentary leishmaniasis; perspectives of new antigens and different diagnostic platforms; molecular tools used in the species-specific diagnosis of leishmaniasis; 10. Challenges for the control of arboviruses of urban occurrence: biological, epidemiological and environmental components; dynamics of transmission in different scenarios; vectors and host susceptibility; 11. Challenges for serological and molecular diagnosis of arbovirus; 12. Immunopathogenic aspects of arboviruses and correlation with clinical manifestations; 13. Traveler’s medicine: critical analysis of prevention measures and chemoprophylaxis Marcos Boulos, Jos_ Angelo Lauletta Lindoso, S_lvia Maria F_tima di Santi 50 MIP5714 5 Elaboration of a project as a mechanism of evaluation of the student’s perception of the importance of each theme presented. Presentation of seminars with discussion of results of published studies http://www.fm.usp.br/en/portal/

HIV / AIDS infection is a serious health problem today and its repercussions are felt in many aspects of human life. Well-conducted scientific research can contribute to the generation of knowledge in coping with this epidemic, focusing on components of the complex network of related biopsychosocial factors. Considering that the technical preparation for the planning and execution of scientific research is essential for the training of the researcher, this discipline intends to offer subsidies to the process of elaboration, reading and critical analysis of research projects applied to the deepening the knowledge regarding HIV infection AIDS, with emphasis on the interdisciplinary approach. A) To discuss the process of scientific investigation that has as object the study of HIV / AIDS infection, including its planning, main approaches, methods and techniques. B) To provide subsidies for the formulation of research projects focused on this theme. C) To enable students to analyze literature about the subject, through a fair interpretation of the most frequently used research methods. D) To stimulate the interdisciplinary approach in scientific research related to HIV / AIDS infection Medical School (FM) São Paulo, Pinheiros campus • Fundamentals of scientific research: observation and experimentation; metering; probability, Induction; • Research planning: the research process; • Selection and formulation of the scientific inquiry of the research; • Bibliographic research survey; • Research planning: study designs applied to HIV / AIDS infection (quantitative observational and intervention studies, qualitative studies); • Selection of subjects for the research: sample calculation and sampling criteria, recruitment of subjects; • Data collection and use of data as a source of information (quality and quantity); • Measurement of results (accuracy); • Planning of the analysis and interpretation of results; • The research report; • Ethical aspects of research involving human beings; • Research funding. Aluisio Augusto Cotrim Segurado, Ana Marli Christovam Sartori, Eliana Battaggia Gutierrez 70 MIP5734 5 The selection of students for the subject will require the submission of scientific research proposal related to HIV / AIDS infection. The evaluation will be based on the attribution of a concept regarding the interest and participation of the students in the proposed activities – classes, seminars, guided exercises, as well as the presentation of an individual research project at the end of the course. http://www.fm.usp.br/en/portal/

The epidemiological methodology, along with its traditional use in the area of Collective Health, has been used as a privileged instrument in conducting clinical research. Epidemiology techniques have been useful in addressing the issues that characterize clinical work, both from the perspective of health services and from scientific research. The aim of this course is to systematize the existing knowledge about the application of this methodology in the development of technical-scientific production in Clinic, as well as in the implementation of its practice. To understand the application of epidemiological methodology in clinical research; To know the basic technical elements for elaboration and conduction of research projects; Encourage the ability to critically evaluate scientific articles published in the medical literature; To provide instruments for the improvement of clinical practice, based on the critical evaluation of the literature. Medical School (FM) São Paulo, Pinheiros campus The course will consist of theoretical classes, seminars and practical classes, covering the following topics: Definition of Epidemiology and its main concepts; Studies on diagnostic tests; Prognostic studies; Experimental Studies; Tracking; Systematic reviews; Critical reading of medical publications; Discussion of research projects in Clinical Epidemiology. Moises Goldbaum, Moacyr Roberto Cuce Nobre, Paulo Rossi Menezes 35 MPR5730 6 The evaluation will consist of attendance, participation and presentation of seminars and individual test. http://www.fm.usp.br/en/portal/

Two aspects justify this discipline. The first one concerns the great demand existing in the HC / FMUSP complex on the debate and understanding of projects / studies that use epidemiological methodology, and articles published in scientific journals. The second aspect concerns the possibility of integrating the different fields and disciplinary areas of research of the complex, facilitating the incorporation and understanding of the methodological instruments by the graduate students and discussing the validity of the use of these instruments in specific researches. Discuss current epidemiological and related issues Analysing the validity of studies using epidemiological methodology Understand subjects relevant to the postgraduate in the health area Medical School (FM) São Paulo, Pinheiros campus The course will be given in the form of seminars. Papers will be analyzed from epidemiological studies or on topics important for research in the health area, published or to be submitted for publication in national and foreign scientific journals, and projects / studies that use epidemiological methodology. Eventually, faculty and researchers from the institution or from other institutions may present a topic related to their area of research. Jose Eluf Neto 25 MPR5749 4 Presentation and participation in seminars http://www.fm.usp.br/en/portal/