Students enrolled in the Graduate Program in Biochemical and Pharmaceutical Technology are of different backgrounds and include pharmacists, biologists, engineers, veterinarians, among others. This course will provide the students a wide view of Biochemical and Pharmaceutical Technology by means of the participation of visiting scientists and professors from other universities of Brazil and from abroad. It will be based on two-weeks intensive courses on frontier topics that may significantly contribute to the Graduate Program internationalization process. To provide the students with broad and up-to-date themes within the fields of Fermentation Technology, Industrial Enzymology, Food Technology and Chemical-Pharmaceutical Technology by means of seminars, intensive courses, conferences and hands-on activities. School of Pharmaceutical Sciences (FCF) São Paulo main campus Seminars and intensive courses will be related to the Areas of Concentration and research lines of the Graduate Program in Biochemical and Pharmaceutical Technology. The Areas of Concentration are: Food Technology, Fermentation Technology and Chemical-Pharmaceutical Technology. Research lines are: Production and conservation of drugs and pharmaceutical goods; Development and optimization of technologies and formulations in food processing; Fermentative and enzymatic processes for the production and application of bioproducts. Joao Carlos Monteiro de Carvalho, Adalberto Pessoa Junior FBT5776 2 http://www.fcf.usp.br/english.php

Besides being administered directly in the form of capsules, probiotic microorganisms are used as food supplements which, together with prebiotic ingredients, constitute the last generation functional foods, leading to beneficial effect on the intestinal microbiota. At the same time, food products such as dairy products and some non-dairy products, such as soy and/ or fruit products, are rich in certain essential health nutrients, such as proteins, calcium, and various vitamins. Technological benefits with respect to the process flow chart and the formulation of these products can also be provided by the use of probiotic cultures. Therefore, the technology used in the manufacture of cheese and other dairy products, as well as other food products involving the addition of these cultures is very promising and should be explored increasingly by the food industry. Provide students with updated concepts on the application of probiotic cultures in food products, taking into account the biological effects and consequences on the production technology and the characteristics of the final product attributed to these microorganisms. School of Pharmaceutical Sciences (FCF) São Paulo main campus 1. Introduction: pharmaceutical and food applications of probiotic cultures; Characterization of the main cultures employed; main biological effects attributed to probiotic cultures 2. Industrial application: effect of milk supplementation; use of co-cultures 3. Flow chart of industrial processes, and physico-chemical, biochemical, nutritional, and microbiological characteristics of the products obtained: use of probiotic cultures in fermented milk and yogurt technology, cheese technology, and technology of some non-dairy products, such as soy products and/ or fruit products 4. Consequences of applying probiotic cultures related to food production procedures 5. Practical activity: production of food using conventional procedures (without supplementation with probiotic cultures) x production of food with probiotic cultures 6. Seminars presented by the students and discussion of scientific papers in the area Susana Marta Isay Saad, Raquel Bedani Salvio 23 FBT5781 4 http://www.fcf.usp.br/english.php

The course aims to put the students in contact with researchers and professionals working in concentration areas of the Program (Clinical Chemistry, Physiopathology and Toxicology) and in related areas with the presentation of seminars on current advanced topics. The faculty includes national and international researchers. The course is offered in the first semester of each year and is mandatory for the all Doctorate students of the Program. This course will permit the students interact with different areas of research making it possible the acquisition of a broad and updated vision of Science in the concentration areas of the Program and in related areas. School of Pharmaceutical Sciences (FCF) S?o Paulo main campus The program will be determined every semester by the invited speakers. Topics will be preferentially include the areas covered by the Program (Clinical Chemistry, Physiopathology and Toxicology) but also related areas. Sabrina Epiphanio 60 FBC5792 1 Course will be taught in Portuguese and English. Participation in class, seminars report, and frequency. http://www.fcf.usp.br/english.php

The course aims to put the students in contact with researchers and professionals working in concentration areas of the Program (Clinical Chemistry, Physiopathology and Toxicology) and in related areas with the presentation of seminars on current advanced topics. The faculty includes national and international researchers. The course is offered in the first semester of each year and is mandatory for the Master and Direct Doctorate students of the Program. This course will permit the students interact with different areas of research making it possible the acquisition of a broad and updated vision of Science in the concentration areas of the Program and in related areas. School of Pharmaceutical Sciences (FCF) S?o Paulo main campus The program will be determined every semester by the invited speakers. Topics will preferentially include the areas covered by the Program (Clinical Chemistry, Physiopathology and Toxicology) but also related areas. Ana Paula de Melo Loureiro, Silvia Berlanga de Moraes Barros 60 FBC5793 1 Course will be taught in Portuguese and English. Participation in class, seminars report, and frequency. http://www.fcf.usp.br/english.php

Many scientific papers are rejected even before they are evaluated by the reviewers. Writing quality and consistent scientific articles can help to reduce this initial rejection in high-impact journals, making the chance for successful publication more effective. Develop skills to write quality scientific reports. School of Pharmaceutical Sciences (FCF) São Paulo main campus Writing the major topics of an article. General advice on writing English and for publication. Article Edition. Practical exemples and writing. Carla Taddei de Castro Neves, Daniel Jay Hoffman 20 FBC5954 1 Article writing. http://www.fcf.usp.br/english.php

Writing is part of Science. Students enrolled in the Graduate Program in Biochemical and Pharmaceutical Technology are of different backgrounds and include pharmacists, biologists, engineers, veterinarians, among others. Nonetheless, all of them have to publish their results. This course focus on preparing original scientific articles. It highlights the importance of publication for an academic career, as well as for scientific development. Basic practices for scientific writing will be provided to stimulate students to publish their results. With this course we intend to increase the number and quality of publications of the students from the Graduate Program in Biochemical and Pharmaceutical Technology, as well as to contribute to the preparation of dissertations and thesis. The course is intended to provide the students with tools to prepare and publish scientific articles, as well as to help with scientific observation, planning and data organizing. Additionally, we expect to promote critical reading of scientific articles and publishing of the results generated by the students during graduate course. The course will also help students in the preparation of dissertations and thesis. School of Pharmaceutical Sciences (FCF) São Paulo main campus Course will include lectures, exercises, case-studies, and practical classes to discuss the manuscripts to be elaborated by each student during the course. 1- Introduction: – Scientific information through the time and the importance of publishing; – Adequate choice of journal for publication; – Types of articles and presentation styles; – Items of each type of article (full paper, short communication and review); – Discussion about Impact Factor (I.S.I. _ Institute for Scientific Information) and journal quality based on Qualis-CAPES classification. 2- The importance of Scientific Reading. Examples of a step-by-step publication process: manuscript preparation, submission, revisions, proof-reading and final article publication. Analysis of accepted and rejected submitted manuscripts. 3- Organizing the results to be published; discussion and objective statement. Preparation of a manuscript outline. 4- Definition of the manuscript title, keywords, authors and affiliations, corresponding author. Study-case of articles published in the journal selected for manuscript submission. 5- Writing of Materials and Methods Section. Units of measurement, precise description of methods. 6- Writing of Results Section. Presentation of figures, tables, flowcharts and schemes. Appropriate Captioning. 7- Writing of Discussion Section. Highlighting the most important results. Identifying and stating the most important findings of the work. 8- Writing of Conclusion Section and the Abstract. Acknowledgements. 9- References and citations. Abbreviations. 10- Writing of an impacting Cover Letter. How to answer the reviewer�fs comments. Adalberto Pessoa Junior, Carlota de Oliveira Rangel Yangui 15 FBT5700 6 Preparation of a manuscript through the course and exercises related to the manuscript preparation. http://www.fcf.usp.br/english.php

This course aims to teach techniques dealing with recombinant DNA and enable the students to perform a number of basic methodologies frequently used in laboratories which research activities in gene expression, molecular cloning and manipulation of DNA and RNA in general. Another goal is to complement informations given in other regular lessons and transmit a global vision to the student. The course is supposed to give postgrad students the opprotunity to acquire knowledge about Plasmodium and apply moleculares techniques. Further, by applying practical techniques, they learn different aspects about Plasmodium biology and malaria disease. In addition, the students Will have the opportunity to present general topics related to malaria in a series of seminars held in English or Portuguese language. Biomedical Sciences Institute (ICB) São Paulo main campus 1) Cloning of different genes encoding antigens of Plasmodium falciparum; 2) Purification of recombinant proteins by affinity chromatography. 3) PCR; 4) SDS-PAGE; 5) Western blotting; 6) ELISA 7) Real time PCR 8) DNA edition soiftare (ApE). The complete methods are provided in a manual which is delivered in the beginning of the course. Gerhard Wunderlich, Carsten Wrenger 2 BMP5785 5 The course is mainly meant for undergrad students in the last semesters of Biology, Biomedicine or Pharmaceutical Sciences. In case that the offered seats are not occupied by undergrad students, the remaining slots can be distributed among interested postgrad students. Before the course, all selected students meet with the professor in order to organize working groups of two students and distribute seminar themes. The course is mainly meant for undergrad students in the last semesters of Biology, Biomedicine or Pharmaceutical Sciences. In case that the offered seats are not occupied by undergrad students, the remaining slots can be distributed among interested postgrad students. Written exam and seminar presentations. https://ww2.icb.usp.br/ing/

Within the strategic objectives of CENA, the “Productivity and Agribusiness Food” includes the programs for plant breeding and production and food preservation, whose scientific research deals in many cases with the use of nuclear techniques in biological systems. The course will provide the basics of different nuclear and related techniques used in developing research on agricultural productivity, aiming to secure and qualitative development of scientific works. Present nuclear and related techniques as tool for studying factors affecting animal productivity and its interaction with the environment, through nutritional evaluation of feeds, the study of nutrient metabolism, quantification and identification of bioactive molecules present in foods and by-products and studies for mitigating greenhouse gases by animals. Center of Nuclear Energy in Agriculture (CENA) Piracicaba campus The use of isotopic markers such as 13C, 51Cr, 32P, 45Ca and 15N and the radiation is discussed in understanding the way as the microorganisms in the rumen of animals digest forages and other foods; how the radiation may increase the digestibility of fibrous foods and how radioisotopes and radiation are important tools for studying the real absorption of minerals; besides being discussed the use of markers such as 125I and 3H for determination of hormones by immunohistochemical analysis to monitor reproductive functions of female domestic interest. It is also studied food and diet regarding the in vivo production of methane produced by ruminants by systems using single chambers and tracer gas SF6. Practical classes will analyze different products to follow techniques of chemical analysis; estimates of total digestible nutrients and gas production in the evaluation of food; Beyond the determination of minimum requirements of minerals in domestic animals; digestibility in vivo and in vitro determination of bioactive molecules in food and quantification of enteric methane. Adibe Luiz Abdalla, Helder Louvani 20 CEN5740 12 Assessment through seminars with the presentation of the results obtained in practical classes. http://www.cena.usp.br/

The contemporary legal theory has reacted to social, economic and political-international movements, through multiple transformations with regards to the theoretical field. Particularly, the general theory of law has faced the transformation of basic and standard categories within the legal system, experiencing the genesis of new forms and instruments of legal liability and sanctioning; new models of normative texture (that go beyond the hard and soft law opposition, to encompass models of mixt law), interpretation and enforcement. Alternative dispute resolution mechanisms have been developed, always with less attachment to state aims of retribution, than the restoration perspective, on the one hand; and always with the purpose to establish alternative instruments of accountability, more attached to the emerging mechanism of Smart Regulation, by another side. The Course is aimed at interdisciplinarity and will foster graduates and researchers to deal with new fields of legal knowledge. The course will be focused on the analysis of recent developments within the theory of law and the legal movements, situated on: (i) the theory of the legal system and its rules; (ii) the theoretical approaches related to deliberative procedures, theory of democracy, systems theory, critical legal studies, theory of legal field, and theories of economy and international relations aimed at law; (iii) the emerging mechanisms of legal regulation in areas of conflict and social tension inside the contemporary society (e.g. Environment and Human Rights); (iv) the convergences and strains between civil law and common law systems. Faculty of Law (FD) S?o Paulo, downtown campus 1. Risk society and Law – current stage of the debate; 2. Democracy and public governance; 3. Private governance and compliance; 4. Critical legal studies and its recent developments; 5. Economy, International Relations and Law; 5. Accountability and risk; 6. Alternative Dispute Resolution; 7. Impact Assessment; 8. Transnationalization and regulatory harmonization; 9. Hard law, soft law and mixt law; 10. New Schemes of Sanction and Accountability; 11. Smart Regulation; 12. Convergences and divergences in the civil law systems and common law systems; 13. Mechanisms of emerging legal regulation in conflict and social tension societies (Environment); 14. Mechanisms of emerging legal regulation in conflict and social tension societies (Human Rights) Rafael Diniz Pucci 35 DFD5922 8 Conceived in a fundamentally interdisciplinary theme, the Course is aimed at graduate students from all areas of legal knowledge. The evaluation will consist of: (a) participation in the activities (e.g. role play and case study); (b) seminars; (c) paper. http://www.law.usp.br/

The growing production of knowledge in the context of aseptic processing of health products and healthcare environment decontamination, such as biofilms, endotoxins, and prion proteins, among organic residue, has required researchers develop suitable study designs. This course proposes to qualify students to develop research projects in the field of Nursing in Central Sterile Service Departments, taking into account the rigor required for producing knowledge in this specialty. • To discuss and analyze different research designs related to the aseptic processing of health products and healthcare environment decontamination, with the goal of broadening students’ information based on the topic so that their practice can be critical and transformative. To mobilize graduate students’ capacity of using and developing research methods suitable for producing new consistent knowledge. School of Nursing (EE) São Paulo, Pinheiros campus 1. Analysis of published studies on the aseptic processing of health products and healthcare environment decontamination. 2. Basic research designs for demonstrating security against the presence of endotoxins, biofilms and microorganisms in processed health products. 3. Analysis of developing research projects about the aseptic processing of health products and healthcare environment decontamination, identifying their theoretical and methodological basis. Kazuko Uchikawa Graziano 27 ENC5932 2 The course lasts one week and meets on 3 consecutive days with 8 hours of work per day. Presentation of and ability to discuss a developing graduate research project, incorporating pertinent suggestions from the course. http://sites.usp.br/ee/

The proposal of this course is to create an adequate infrastructure for data collection and management of the studies carried out in the scope of Post-Graduation Program. In order to achieve this goal, students will have access to the world’s most widely used system for electronic data collection and data management in scientific research, known as REDCap (Research Electronic Data Capture). This course will provide best practices and real case examples for data management in REDCap. This course aims to present critical concepts and practical methods to support planning, collection, storage, and dissemination of data in clinical research to enhance security, reliability and quality to the data collected for research purposes. School of Nursing (EE) São Paulo, Pinheiros campus Principles of data management in scientific research; Recommended practices for development of questionnaires; Modalities for data collection in scientific research; Privacy, confidentiality and data security requirements of human research data; REDCap _ key concepts and applications in scientific research; International data standards and best practices for data dictionaries definitions; Effective data management: reports, data export, graphical visualization and data quality monitoring; Considerations for conducting web-based surveys; Hands-on training: REDCap projects development (classical and longitudinal) and application of the main REDCap features. Katia Regina da Silva 20 ENC5966 2 Hands-on exercises. http://sites.usp.br/ee/

All research is grounded in a theoretical perspective. Nursing knowledge is only built through the development and testing of theories and conceptual frameworks. The purpose of this course is to enhance students understanding of how nursing conceptual frameworks are used to guide nursing research. Students will be able to aplly the knowledge learned in this course to guide their proposed research. 1. Describe the relationship between nursing science, philosophy, theory development and research; 2. Examine selected nursing theories and their application to research; 3. Apply the process of theoretical substruction in the analysis of nursing theory testing research. School of Nursing (EE) São Paulo, Pinheiros campus Structure of knowledge in the discipline of nursing; The value and purpose of nursing theory; Tipes of theories; Selected conceptual frameworks and nursing theories and their application to guide research; Theoretical substraction of nursing theories. Rita de Cassia Gengo e Silva 22 ENC5967 2 Each student will select a published nursing theory testing research article and complete a theoretical substraction on the conceptual framework of the study. http://sites.usp.br/ee/