A Microbiome is a complex microbial community, which can inhabit a wide variety of environments, from the human gut, to soil, to food products. The study of these communities is done through Next Generation Sequencing, and its associated metadata. There is a large demand to have people correctly trained that can perform this analysis. This class will supply this demand by introducing the students to current analytical tools used for microbiome data analysis, through theoretical and practical classes, which will enable the student to conduct a final data analysis project (primary data or database available data). To provide theory and practical background on conducting microbiome data analysis. School of Pharmaceutical Sciences (FCF) São Paulo main campus Fundamentals concepts in microbiome related experimental design, fundamentals of sequencing library preparation, introduction to data analysis using Qiime, Picrust, Permanova, R, A’nvio etc. Christian Hoffmann 20 FBA5906 6 The class will be thought in English and may have the participation of invited international data analysts, to be announced opportunely. Students will be required to hand in a final paper based on the analysis they conduct throughout the semester. http://www.fcf.usp.br/english.php

This course aims to teach techniques dealing with recombinant DNA and enable the students to perform a number of basic methodologies frequently used in laboratories which research activities in gene expression, molecular cloning and manipulation of DNA and RNA in general. Another goal is to complement informations given in other regular lessons and transmit a global vision to the student. The course is supposed to give postgrad students the opprotunity to acquire knowledge about Plasmodium and apply moleculares techniques. Further, by applying practical techniques, they learn different aspects about Plasmodium biology and malaria disease. In addition, the students Will have the opportunity to present general topics related to malaria in a series of seminars held in English or Portuguese language. Biomedical Sciences Institute (ICB) São Paulo main campus 1) Cloning of different genes encoding antigens of Plasmodium falciparum; 2) Purification of recombinant proteins by affinity chromatography. 3) PCR; 4) SDS-PAGE; 5) Western blotting; 6) ELISA 7) Real time PCR 8) DNA edition soiftare (ApE). The complete methods are provided in a manual which is delivered in the beginning of the course. Gerhard Wunderlich, Carsten Wrenger 2 BMP5785 5 The course is mainly meant for undergrad students in the last semesters of Biology, Biomedicine or Pharmaceutical Sciences. In case that the offered seats are not occupied by undergrad students, the remaining slots can be distributed among interested postgrad students. Before the course, all selected students meet with the professor in order to organize working groups of two students and distribute seminar themes. The course is mainly meant for undergrad students in the last semesters of Biology, Biomedicine or Pharmaceutical Sciences. In case that the offered seats are not occupied by undergrad students, the remaining slots can be distributed among interested postgrad students. Written exam and seminar presentations. https://ww2.icb.usp.br/ing/

Within the strategic objectives of CENA, the “Productivity and Agribusiness Food” includes the programs for plant breeding and production and food preservation, whose scientific research deals in many cases with the use of nuclear techniques in biological systems. The course will provide the basics of different nuclear and related techniques used in developing research on agricultural productivity, aiming to secure and qualitative development of scientific works. Present nuclear and related techniques as tool for studying factors affecting animal productivity and its interaction with the environment, through nutritional evaluation of feeds, the study of nutrient metabolism, quantification and identification of bioactive molecules present in foods and by-products and studies for mitigating greenhouse gases by animals. Center of Nuclear Energy in Agriculture (CENA) Piracicaba campus The use of isotopic markers such as 13C, 51Cr, 32P, 45Ca and 15N and the radiation is discussed in understanding the way as the microorganisms in the rumen of animals digest forages and other foods; how the radiation may increase the digestibility of fibrous foods and how radioisotopes and radiation are important tools for studying the real absorption of minerals; besides being discussed the use of markers such as 125I and 3H for determination of hormones by immunohistochemical analysis to monitor reproductive functions of female domestic interest. It is also studied food and diet regarding the in vivo production of methane produced by ruminants by systems using single chambers and tracer gas SF6. Practical classes will analyze different products to follow techniques of chemical analysis; estimates of total digestible nutrients and gas production in the evaluation of food; Beyond the determination of minimum requirements of minerals in domestic animals; digestibility in vivo and in vitro determination of bioactive molecules in food and quantification of enteric methane. Adibe Luiz Abdalla, Helder Louvani 20 CEN5740 12 Assessment through seminars with the presentation of the results obtained in practical classes. http://www.cena.usp.br/

The contemporary legal theory has reacted to social, economic and political-international movements, through multiple transformations with regards to the theoretical field. Particularly, the general theory of law has faced the transformation of basic and standard categories within the legal system, experiencing the genesis of new forms and instruments of legal liability and sanctioning; new models of normative texture (that go beyond the hard and soft law opposition, to encompass models of mixt law), interpretation and enforcement. Alternative dispute resolution mechanisms have been developed, always with less attachment to state aims of retribution, than the restoration perspective, on the one hand; and always with the purpose to establish alternative instruments of accountability, more attached to the emerging mechanism of Smart Regulation, by another side. The Course is aimed at interdisciplinarity and will foster graduates and researchers to deal with new fields of legal knowledge. The course will be focused on the analysis of recent developments within the theory of law and the legal movements, situated on: (i) the theory of the legal system and its rules; (ii) the theoretical approaches related to deliberative procedures, theory of democracy, systems theory, critical legal studies, theory of legal field, and theories of economy and international relations aimed at law; (iii) the emerging mechanisms of legal regulation in areas of conflict and social tension inside the contemporary society (e.g. Environment and Human Rights); (iv) the convergences and strains between civil law and common law systems. Faculty of Law (FD) S?o Paulo, downtown campus 1. Risk society and Law – current stage of the debate; 2. Democracy and public governance; 3. Private governance and compliance; 4. Critical legal studies and its recent developments; 5. Economy, International Relations and Law; 5. Accountability and risk; 6. Alternative Dispute Resolution; 7. Impact Assessment; 8. Transnationalization and regulatory harmonization; 9. Hard law, soft law and mixt law; 10. New Schemes of Sanction and Accountability; 11. Smart Regulation; 12. Convergences and divergences in the civil law systems and common law systems; 13. Mechanisms of emerging legal regulation in conflict and social tension societies (Environment); 14. Mechanisms of emerging legal regulation in conflict and social tension societies (Human Rights) Rafael Diniz Pucci 35 DFD5922 8 Conceived in a fundamentally interdisciplinary theme, the Course is aimed at graduate students from all areas of legal knowledge. The evaluation will consist of: (a) participation in the activities (e.g. role play and case study); (b) seminars; (c) paper. http://www.law.usp.br/

The growing production of knowledge in the context of aseptic processing of health products and healthcare environment decontamination, such as biofilms, endotoxins, and prion proteins, among organic residue, has required researchers develop suitable study designs. This course proposes to qualify students to develop research projects in the field of Nursing in Central Sterile Service Departments, taking into account the rigor required for producing knowledge in this specialty. • To discuss and analyze different research designs related to the aseptic processing of health products and healthcare environment decontamination, with the goal of broadening students’ information based on the topic so that their practice can be critical and transformative. To mobilize graduate students’ capacity of using and developing research methods suitable for producing new consistent knowledge. School of Nursing (EE) São Paulo, Pinheiros campus 1. Analysis of published studies on the aseptic processing of health products and healthcare environment decontamination. 2. Basic research designs for demonstrating security against the presence of endotoxins, biofilms and microorganisms in processed health products. 3. Analysis of developing research projects about the aseptic processing of health products and healthcare environment decontamination, identifying their theoretical and methodological basis. Kazuko Uchikawa Graziano 27 ENC5932 2 The course lasts one week and meets on 3 consecutive days with 8 hours of work per day. Presentation of and ability to discuss a developing graduate research project, incorporating pertinent suggestions from the course. http://sites.usp.br/ee/

The goal of every astrophysical model is to provide a quantitative interpretation of astrophysical observations. This discipline is hence fundamental to students which aim to pursue their MSc, PhD and post-graduate studies in Astrophysics. Study the basic processes involved in the production of radiation that we receive from celestial bodies, as well as the interaction of this radiation with intervening matter. Institute of Astronomy, Geophysics and Atmospheric Sciences (IAG) São Paulo main campus Radiative Transfer. Radiation fields. Polarization of Light. Radiation from charged particles. System of Particles. Special Relativity. Bremsstrahlung. Synchrotron Radiation. Compton Scattering. Plasma Effects. Atomic radiative and collisional transitions. Astrophysical line emission processes. Stellar spectral line formation. Antonio Mario Magalhaes 30 AGA5731 11 http://www.iag.usp.br/international/

The aim of this course is the study of stellar populations in our Galaxy, and in other galaxies. The populations in our Galaxy, from the halo, bulge, thin and thick disks, can be studied in terms of their ages, metallicities, abundances, kinematics, and their evolution in time and space. We also introduce the basic ingredients of evolution of galaxies: stellar evolution, chemical evolution, and spectroscopy of individual stars and composite stellar populations. Different types of galaxies are studied: elliptical, spiral, irregular galaxies, and HII regions. The program is concluded with the analysis of composite spectra of galaxies, using codes from the literature. The distribution of stellar populations in galaxies is studied, making that these studies comprehend most objects in the Universe: the galaxies studied through the stars that form them. In astrophysics, it is therefore a fundamental course. Institute of Astronomy, Geophysics and Atmospheric Sciences (IAG) São Paulo main campus Basics of stellar evolution. Basics of nucleosynthesis. Formation and abundances of chemical elements. Basics of stellar dynamics. Models of chemical evolution of the Galaxy and galaxies in general. Evolution of stellar populations in the Galaxy. Star formation rate in galaxies, initial mass function. Stellar population synthesis and the Hubble diagram. Spectroscopy of composite stellar populations. Stellar populations in spiral, elliptical, lenticular, irregular and spheroidal dwarf galaxies. Beatriz Leonor Silveira Barbuy 25 AGA5740 11 http://www.iag.usp.br/international/

The observational activity is one of the pillars of Astrophysics, continuously feeding the theoretical elaboration. Observational training is essential both to researchers who produce the data as to theorists who should know evaluate them critically. Give to the graduate student fundamental notions of the instrumentation used in Astrophysics, as well as on observational techniques, data acquisition and reduction. In particular, give to the student conditions to plan the use of instrumentation to achieve specific scientific goals. Institute of Astronomy, Geophysics and Atmospheric Sciences (IAG) São Paulo main campus Effect of Earth’s atmosphere on observations in the optical and infrared; Telescopes and image quality; Effects of the interstellar medium; Detectors; Techniques of radio astronomy; Photometry; Spectroscopy; Elements of polarimetry ; Data acquisition handling; Space astronomy – X-rays Roberto Dell’Aglio Dias da Costa, Marcos Perez Diaz, Jorge Luis Melendez Moreno 30 AGA5802 11 Tests and practical exercises http://www.iag.usp.br/international/

In this course we will discuss the main scenarios for the formation and evolution of galaxies in order to enable the students to know the main recent advances in the area and also to expose them to the questions and challenges still open. Some content discussed in other disciplines, especially Extragalactic Astronomy, will be briefly reviewed. The question of the origin and evolution of galaxies is one of the most important research topics in the present day in extragalactic astronomy and cosmology, both theoretically and observationally. The techniques used are quite varied and useful in various areas of research. The course should provide the elements for students to track progress in this area Institute of Astronomy, Geophysics and Atmospheric Sciences (IAG) São Paulo main campus Review of the properties of galaxies: structure, stellar populations, scale relations, dependence on the environment. Review of cosmology concepts relevant to the course. Gravity instability and structure formation. The first stars. The reionization. Semi-analytical models of galaxy formation. Star formation. Chemical evolution. Photometric-photometric evolution. Mergers of galaxies. Evolution of Morphology. Analysis of observational data. Laerte Sodre Junior, Gastao Cesar Bierrenbach Lima Neto, Paula Rodrigues Teixeira Coelho 25 AGA5906 11 http://www.iag.usp.br/international/

This course deals with formation models for the main geotectonic provinces, how they are set in the past and in the present; the main characteristics of the continental and oceanic lithosphere using geophysical data and how to integrate this data to the tectonic knowledge of South American plate. This course aims to provide information on the main geotectonic provinces of South America and about the geophysical surveys in great scale. It is expected that the students can use all the information to infer relations among geology and geophysics. Institute of Astronomy, Geophysics and Atmospheric Sciences (IAG) São Paulo main campus 1. South American plate contextualization. 2. Continental and oceanic lithosphere. 3. Craton: concept and examples, South American Cratons. 4. Orogens: concept and examples; mobile belts: BSB, Paraguay-Araguaia, Mantiqueira, Borborema. 5. Patagonia. 6. Andes. 7. Basin: formation basic concepts; South American basins: Paran_, Chaco, Potiguar, Santos, Rec_ncavo- Tucano, Magalh_es. 8. Oceanic lithosphere. 9. Paleomagnetism. 10. Heat flow. 11. Crust and lithosphere thickness. 12. Effective lithosphere thickness. 13. Geoid. 14. Gravity. 15. Magnetic field. 16. Stress. 17. Seismicity at the South American and Nazca plates. Marta Silvia Maria Mantovani, Yara Regina Marangoni, Ricardo Ivan Ferreira da Trindade 30 AGG5937 9 Tests and seminars. http://www.iag.usp.br/international/

Phycology is a broad area that studying a wide diversity of life forms, from prokaryotic organisms (cyanobacteria) to different lineages of eukaryotes. The knowledge about biodiversity, biology and biotechnological applications have advanced intensively in recent years in Brazil and abroad. Therefore, the focus of this course is to keep the graduate students aware of these advances, and promote presentations and discussions of diverse phycological topics in English. 1. Present and discuss phycological topics and related areas in order to provide a broad and updated knowledge to the students. 2. Expose research projects and seminars for discussion and suggestions, enabling the exchange of information between the projects developed by the students. 3. Offer the student an environment for training oral presentations and scientific debates in English. Institute of Biosciences (IB) São Paulo main campus Diverse and current themes on Phycology and related areas, including classical and molecular taxonomy and systematics, biogeography and phylogeny, ecology, physiology, chemistry, genetics, omics sciences, mariculture, environmental education and biotechnological applications of algae. The course will be based on oral presentation of seminars and discussions. Mariana Cabral de Oliveira, Fanly Fungyi Chow Ho 20 BIB5755 2 All students should present at least one seminar in English (including the oral presentation and slides) based on their research project or a related subject. http://www.ib.usp.br/en/

Integrate concepts from different areas of plant biology and update about the last generation experimental approaches Improve the knowledge about current topics, experimental approaches and techniques in plant biology Institute of Biosciences (IB) São Paulo main campus The subject will approach theoretical topics about gene expression regulation, genetic transformation, molecular markers, genomics, genetic and metabolic engineering, as long as technical aspects. The content will be introduced from the system biology point of view in an integrative and interdisciplinary manner, aiming the understanding of physiological and breeding processes Marie Anne van Sluys, Maria Magdalena Rossi 20 BIB5764 8 Class participation, lectures and tests http://www.ib.usp.br/en/